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A New Facile Route to Chlorination of Alcohols via Lewis Acid AlCl<sub>3</sub>
Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
- 1 Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
- 2 Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
- 3 Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
- 4 Key Laboratory of Polymer Materials of Gansu Province, Key Laboratory of Eco-Environment-Related Polymer Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, China
International Journal of Organic Chemistry·Volume 02 (2012)·Pages 21–25·Published 15 March 2012·DOI10.4236/ijoc.2012.21004
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Abstract
Halogenated aluminates AlCl 3 , applied as efficient chlorination reagent for hydroxyl groups of substitution alcohols is described. Primary and secondary benzylic alcohols could be transformed into corresponding aromatic halides with almost complete conversion and unique selectivity. As chlorination reagent, AlCl 3 has an incomparable advantage over others, such as low material cost, commercial availability as well as convenient product isolation.
KeywordsAlcoholsLewis AcidNucleophilesChlorination
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