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KF-Al2O3 as an Efficient and Recyclable Basic Catalyst for the Synthesis of 4H-Pyran-3-carboxylates and 5-Acetyl-4H-pyrans

¹ Department of Chemistry, North-Eastern Hill University (NEHU), Shillong, India
² Department of Chemistry, North-Eastern Hill University (NEHU), Shillong, India
³ Department of Chemistry, North-Eastern Hill University (NEHU), Shillong, India
⁴ Department of Chemistry, North-Eastern Hill University (NEHU), Shillong, India

International Journal of Organic Chemistry·Volume 02 (2012)·Pages 282–286·Published 25 September 2012·DOI10.4236/ijoc.2012.23038

Abstract

KF-Al 2 O 3 as a recyclable basic catalyst for the three-component synthesis of 4 H -pyran derivatives by the reaction of aldehydes, malononitrile and active methylene dicarbonyl compounds in ethanol at room temperature is described. The protocol is environmentally benign and offers rapid access to a wide array of 4 H -pyran heterocycles in good to excellent yields.

Keywords4H-Pyran derivativesEthanolKF-Al&ltsub&gt2&lt/sub&gtO&ltsub&gt3&lt/sub&gtRoom TemperatureThree-Component

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KF-Al<sub>2</sub>O<sub>3</sub> as an Efficient and Recyclable Basic Catalyst for the Synthesis of 4<i>H</i>-Pyran-3-carboxylates and 5-Acetyl-4<i>H</i>-pyrans

Abstract

References (23)