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Ultrasonically Assisted Synthesis of Aromatic Sulfonic Acids under Vilsmeier Haack Conditions in Acetonitrile Medium
Department of Chemistry, Osmania University, Hyderabad, India
Department of Chemistry, Osmania University, Hyderabad, India
Department of Chemistry, Osmania University, Hyderabad, India
Department of Chemistry, Osmania University, Hyderabad, India
- 1 Department of Chemistry, Osmania University, Hyderabad, India
- 2 Department of Chemistry, Osmania University, Hyderabad, India
- 3 Department of Chemistry, Osmania University, Hyderabad, India
- 4 Department of Chemistry, Osmania University, Hyderabad, India
International Journal of Organic Chemistry·Volume 02 (2012)·Pages 336–340·Published 27 December 2012·DOI10.4236/ijoc.2012.24046
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Abstract
Sulfonation of aromatic compounds (Phenols, Anilines) is triggered by Vilsmeier Haack (VH) reagent (DMF/POCl 3 ) or (DMF/SOCl 2 ) in the presence of NaHSO 3 under Sonication and conventional stirred conditions at room temperature. The reactions afforded corresponding Sulfonic acid derivatives in very good yields. The results obtained under Sonication were enhanced when compared with the yields of the conventional method.
KeywordsVilsmeier Haack (VH) ReagentSulfonationNaHSO<sub>3</sub>SonicationAromatic Compounds
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