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Asymmetric Reductive Amination of Carbonyl Compounds by Using<i> N,N,N</i>-Tributylpropanaminium Based Novel Chiral Ionic Liquid
School of Agriculture, Environmental Studies, Indira Gandhi National Open University, New Delhi, India
Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi, India
Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi, India
- 1 School of Agriculture, Environmental Studies, Indira Gandhi National Open University, New Delhi, India
- 2 Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi, India
- 3 Department of Chemistry, Sri Venkateswara College, University of Delhi, New Delhi, India
International Journal of Organic Chemistry·Volume 03 (2013)·Pages 190–193·Published 27 August 2013·DOI10.4236/ijoc.2013.33024
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Abstract
Asymmetric reductive amination of carbonyl compounds was carried out using a novel class of aliphatic quarternary ammonium based chiral ionic liquid. S-(+)-2,3-dihydroxy- N , N , N -tributylpropanaminum bromide chiral ionic liquid has been synthesized, characterized and used for asymmetric reductive amination of carbonyl compounds in the presence of sodium borohydride. These preliminary results are encouraging and advocate dual role of novel ionic liquid as a medium and reducing agent for proficient conversion of ketones to amines, however, reductive amination reaction needs to be established for other substituents.
KeywordsIonic LiquidAsymmetric Reductive AminationChiralCarbonyl Compounds
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