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The Effective Catalyst (Cobalt Salt/Lewis Acid) for Beckmann Rearrangement of Cycloalkanone Oximes to Lactams under Mild Conditions
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
Ube Laboratory, Ube Industries, Ltd., Ube, Japan
Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 1 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 2 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 3 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 4 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 5 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
- 6 Ube Laboratory, Ube Industries, Ltd., Ube, Japan
- 7 Graduate School of Science and Engineering, Yamaguchi University, Ube, Japan
International Journal of Organic Chemistry·Volume 05 (2015)·Pages 57–62·Published 25 May 2015·DOI10.4236/ijoc.2015.52007
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Abstract
The Beckmann rearrangement of cyclohexanone oxime was achieved by the combined use of cobalt salt and Lewis acids co-catalysts (each 10 mol%). Various combinations of cobalt salts and Lewis acids gave lactams in a satisfactory yield under mild conditions. This method makes it possible to reduce undesirable byproducts.
KeywordsBeckmann RearrangementCycloalkanone OximesLactamCobalt CatalystsLewis Acids
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