Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions — Oak Academic Publishing
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Green and High Efficient Synthesis of 2-Aryl Benzimidazoles: Reaction of Arylidene Malononitrile and 1,2-Phenylenediamine Derivatives in Water or Solvent-Free Conditions
Faculty of Chemistry, Kharazmi University, Tehran, Iran
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Faculty of Chemistry, Kharazmi University, Tehran, Iran
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School of Chemistry, College of Science, University of Tehran, Tehran, Iran
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Department of Chemistry, Tarbiat Modares University, Tehran, Iran
1 Faculty of Chemistry, Kharazmi University, Tehran, Iran
2 Faculty of Chemistry, Kharazmi University, Tehran, Iran
3 School of Chemistry, College of Science, University of Tehran, Tehran, Iran
4 Department of Chemistry, Tarbiat Modares University, Tehran, Iran
A fast, high efficiency and environmentally friendly procedure for the synthesis of 2-aryl benzim-idazole derivatives has been reported. Reaction between 1,2-phenylenediamine derivatives and arylidene malononitrile under aqueous media and also solvent-free conditions generates 2-aryl benzimidazole derivatives with a high yield.
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