Preliminary Investigation on the Chemical Constituents and Antioxidant Activities of Two <i>Phellinus</i> Mushrooms Collected in Foshan
- 1 Department of Chemical Engineering, Foshan University, Foshan, China
- 2 School of Life Science and Engineering, Foshan University, Foshan, China
- 3 Department of Chemical Engineering, Foshan University, Foshan, China
- 4 Department of Chemical Engineering, Foshan University, Foshan, China
- 5 Department of Chemical Engineering, Foshan University, Foshan, China
- 6 Department of Chemical Engineering, Foshan University, Foshan, China
Abstract
The Phellinus mushrooms have been known for its immunomodulatory, hypolipidemic, and anticancer activities. In the current work, the chemical constituents of two Phellinus mushrooms, Phellinus pini 141016# and Phellinus sp. 150802#, which were collected in Foshan city, Guangdong province, were investigated preliminarily by pre-test tube method and by comparison with the known natural compounds from Phellinus pini , and their antioxidant activities were evaluated by the biochemical assay of hydroxyl and 2,2-diphenyl-1-pricylhydrazyl (DPPH) radicals scavenging activity in vitro . The results show that both the two Phellinus mushrooms contain phenolics, alkaloids, lactones, steroids and terpenoids, and have potent antioxidant activities. The IC 50 values of DPPH radicals and hydroxyl radicals for Phellinus pini 141016# were 74.37 μg/mL and 59.69 μg/mL, respectively, and the IC 50 values of DPPH radicals and hydroxyl radicals for Phellinus sp. 150802# were 98.95 μg/mL and 165.47 μg/mL, respectively. They are comparable to the antioxidant activity of the standard antioxidant ascorbic acid.
- Kozarski, M., Klaus, A., Jakovljevic, D., Todorovic, N., Vunduk, J., Petrovic, P., Niksic, M., Vrvic, M.M. and van Griensven, L. (2015) Antioxidants of Edible Mushrooms. Molecules, 20, 19489-19525. https://doi.org/10.3390/molecules201019489
- Seephonkai, P., Samchai, S., Thongsom, A., Sunaart, S., Kiemsanmuang, B. and Chakuton, K. (2011) DPPH Radical Scavenging Activity and Total Phenolics of Phellinus Mushroom Extracts Collected from Northeast of Thailand. Chinese Journal of Natural Medicines, 9, 441-445.
- Qi, Y.D., Wu, M.Y. and Shen, R. (2015) Research Advance of Phellinus pini. Forest By-Product and Speciality in China, No. 6, 83-85.
- Du, L.M., Han, R., An, T.C., Shang, X.F. and Wang, J.S. (2014) Resource and Effect of Medical Fungi Phellinus pini (Fr.) Quél. in Shanxi Province. Modern Agricultural Science & Technology, No. 7, 119-120.
- Dai, Y.C. and Yang, Z.L. (2008) A Revised Checklist of Medicinal Fungi in China. Mycosystema, 27, 801-824.
- Xue, M. and Wang, Q.Y. (2004) Chemical Constituents and Biological Activities of the Phellinus Mushroom. World Phytomedicines, 19, 103-105.
- Xu, S.Y., Jin, M.H., Zhao, L.Y., Li, J.J., Wei, Y., Jiang, Z.F., Luo, Q. and Chen, X.H. (2014) Study on the Chemical Components and Acute Toxicological Evaluation of Wild Russula sp. from Meixian County, Guangdong Province. Food Research and Development, 35, 24-26.
- Wu, J.S. and Zhu, F. (2016) Chemical Constituents Pre-Analysis and Antioxidant Activity of the Puffball Calvatia candida from Foshan. Journal of Organic Chemistry Research, 4, 69-76. https://doi.org/10.12677/JOCR.2016.43010
- Lourenco, A., Lobo, A.M., Rodriguez, B. and Jimeno, M.L. (1996) Ceramides from the Fungus Phellinus pini. Phytochemistry, 43, 617-620. https://doi.org/10.1016/0031-9422(96)00335-4
- Ayer, W.A., Muir, D.J. and Chakravarty, P. (1996) Phenolic and Other Metabolites of Phellinus pini, a Fungus Pathogenic to Pine. Phytochemistry, 42, 1321-1324. https://doi.org/10.1016/0031-9422(96)00125-2
- Wangun, H.V.K. and Hertweck, C. (2007) Squarrosidine and Pinillidine: 3,3’-Fused Bis(Styrylpyrones) from Pholiota squarrosa and Phellinus pini. European Journal of Organic Chemistry, 2007, 3292-3295. https://doi.org/10.1002/ejoc.200700090
- Jang, H.J. and Yang, K.S. (2011) Inhibition of Nitric Oxide Production in RAW 264.7 Macrophages by Diterpenoids from Phellinus pini. Archives of Pharmacal Research, 34, 913-917. https://doi.org/10.1007/s12272-011-0608-z