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Studies and Mechanism of Olefination Reaction in Aryl-Enolates with Paraformaldehyde
Centro de Investigación en Ciencias-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
Centro Universitario de Ciencias Exactas e Ingenierías, Departamento de Química, Universidad de Guadalajara, Guadalaja, México
Centro de Investigación en Ciencias-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
- 1 Centro de Investigación en Ciencias-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
- 2 Centro Universitario de Ciencias Exactas e Ingenierías, Departamento de Química, Universidad de Guadalajara, Guadalaja, México
- 3 Centro de Investigación en Ciencias-IICBA, Universidad Autónoma del Estado de Morelos, Cuernavaca, México
International Journal of Organic Chemistry·Volume 09 (2019)·Pages 10–22·Published 11 January 2019·DOI10.4236/ijoc.2019.91002
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Abstract
A simple, efficient and low-cost methodology for the synthesis of α -aryl- α , β -unsaturated esters using paraformaldehyde as a source of carbon was developed. Factors that control reaction yields such as temperature, concentration and reaction time were evaluated. A mechanism is proposed based on experimental structures of the intermediates.
KeywordsOlefinationParaformaldehyde<i>α</i>-Aryl-<i>αβ</i>-Unsaturated Ester<i>α</i>-Methylenation
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