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Central Brain Herniation Secondary to Influenza-Related Encephalopathy in a Pontocerebellar Hypoplasia Child: A Case Report and Review
Department of Pediatric Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Pediatric Emergency, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Surgery, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Pediatric Neurology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Pediatric Emergency, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Neuroelectrophysiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Department of Pediatric Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 1 Department of Pediatric Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 2 Department of Pediatric Emergency, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 3 Department of Surgery, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 4 Department of Pediatric Neurology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 5 Department of Pediatric Emergency, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 6 Department of Neuroelectrophysiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
- 7 Department of Pediatric Radiology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China
Journal of Behavioral and Brain Science·Volume 10 (2020)·Pages 257–264·Published 2 June 2020·DOI10.4236/jbbs.2020.106016
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Abstract
Influenza-associated encephalopathy (IAE) can perform as varying patterns of neuroimaging. Central brain herniation (CBH) secondary to IAE is rare; it may be a bad prognosis. Here, we presented a 4-year-old girl with influenza who had a pontocerebellar hypoplasia (PCH) history; she performed the second Magnetic Resonance Imaging (MRI) on Day 6 from onset, showed the diffuse edema and the occurrence of central herniation; the medulla was “Z-like” folded and the basal cisterns were obliterated completely. Finally she was declared dead. The imbalance between supratentorial and infratentorial pressure can lead to the occurrence of CBH. Severe edema relates to IAE and unstable structure of the posterior fossa might be the main reason for the herniation. MRI is helpful in early diagnosis. Early treatment of cerebral edema in patients with congenital abnormalities of the posterior fossa is vital for their management.
KeywordsPontocerebellar HypoplasiaCentral Brain HerniationInfluenza-Related EncephalopathyMagnetic Resonance Imaging
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