The menstrual cycle has been a topic of interest in relation to behavior and cognition for many years, with historical beliefs associating it with cognitive impairment. However, recent research has challenged these beliefs and suggested potential positive effects of the menstrual cycle on cognitive performance. Despite these emerging findings, there is still a lack of consensus regarding the impact of the menstrual cycle on cognition, particularly in domains such as spatial reasoning, visual memory, and numerical memory. Hence, this study aimed to explore the relationship between the menstrual cycle and cognitive performance in these specific domains. Previous studies have reported mixed findings, with some suggesting no significant association and others indicating potential differences across the menstrual cycle. To contribute to this body of knowledge, we explored the research question of whether the menstrual cycles have a significant effect on cognition, particularly in the domains of spatial reasoning, visual and numerical memory in a regionally diverse sample of menstruating females. A total of 30 menstruating females from mixed geographical backgrounds participated in the study, and a repeated measures design was used to assess their cognitive performance in two phases of the menstrual cycle: follicular and luteal. The results of the study revealed that while spatial reasoning was not significantly related to the menstrual cycle (p = 0.256), both visual and numerical memory had significant positive associations (p < 0.001) with the luteal phase. However, since the effect sizes were very small, the importance of this relationship might be commonly overestimated. Future studies could thus entail designs with larger sample sizes, including neuro-biological measures of menstrual stages, and consequently inform competent interventions and support systems.
Frank, R.T. (1931) The Hormonal Causes of Premenstrual Tension. Archives of Neurology and Psychiatry , 26, 1053-1057. https://doi.org/10.1001/archneurpsyc.1931.02230110151009
Sommer, B. (1992) Cognitive Performance and the Menstrual Cycle. In: Contributions to Psychology and Medicine , Springer, 39-66. https://doi.org/10.1007/978-1-4613-9148-7_2
Richardson, J.T. (1991) Cognition, Memory, and the Menstrual Cycle. Current Psychology of Cognition , 11, 3-26.
Rippon, G. (2019) Her Raging Hormones. In: The Gendered Brain : The New Neuroscience That Shatters the Myth of the Female Brain , The Bodley Head, 25-44.
Moos, R.H. (1968) The Development of a Menstrual Distress Questionnaire. Psychosomatic Medicine , 30, 853-867. https://doi.org/10.1097/00006842-196811000-00006
Toffoletto, S., Lanzenberger, R., Gingnell, M., Sundström-Poromaa, I. and Comasco, E. (2014) Emotional and Cognitive Functional Imaging of Estrogen and Progesterone Effects in the Female Human Brain: A Systematic Review. Psycho Neuroendocrinology , 50, 28-52. https://doi.org/10.1016/j.psyneuen.2014.07.025
Leeners, B., Kruger, T.H.C., Geraedts, K., Tronci, E., Mancini, T., Ille, F., et al . (2017) Lack of Associations between Female Hormone Levels and Visuospatial Working Memory, Divided Attention and Cognitive Bias across Two Consecutive Menstrual Cycles. Frontiers in Behavioral Neuroscience , 11, Article 120. https://doi.org/10.3389/fnbeh.2017.00120
Kozaki, T. and Yasukouchi, A. (2009) Sex Differences on Components of Mental Rotation at Different Menstrual Phases. International Journal of Neuroscience , 119, 59-67. https://doi.org/10.1080/00207450802480101
Mordecai, K.L., Rubin, L.H. and Maki, P.M. (2008) Effects of Menstrual Cycle Phase and Oral Contraceptive Use on Verbal Memory. Hormones and Behavior , 54, 286-293. https://doi.org/10.1016/j.yhbeh.2008.03.006
Schöning, S., Engelien, A., Kugel, H., Schäfer, S., Schiffbauer, H., Zwitserlood, P., et al . (2007) Functional Anatomy of Visuo-Spatial Working Memory during Mental Rotation Is Influenced by Sex, Menstrual Cycle, and Sex Steroid Hormones. Neuropsychologia , 45, 3203-3214. https://doi.org/10.1016/j.neuropsychologia.2007.06.011
Zhu, X., Kelly, T.H., Curry, T.E., Lal, C. and Joseph, J.E. (2015) Altered Functional Brain Asymmetry for Mental Rotation. Neuro Report , 26, 814-819. https://doi.org/10.1097/wnr.0000000000000429
Courvoisier, D.S., Renaud, O., Geiser, C., Paschke, K., Gaudy, K. and Jordan, K. (2013) Sex Hormones and Mental Rotation: An Intensive Longitudinal Investigation. Hormones and Behavior , 63, 345-351. https://doi.org/10.1016/j.yhbeh.2012.12.007
Maki, P.M., Rich, J.B. and Shayna Rosenbaum, R. (2002) Implicit Memory Varies across the Menstrual Cycle: Estrogen Effects in Young Women. Neuropsychologia , 40, 518-529. https://doi.org/10.1016/s0028-3932(01)00126-9
Ferree, N.K., Kamat, R. and Cahill, L. (2011) Influences of Menstrual Cycle Position and Sex Hormone Levels on Spontaneous Intrusive Recollections Following Emotional Stimuli. Consciousness and Cognition , 20, 1154-1162. https://doi.org/10.1016/j.concog.2011.02.003
Ikarashi, K., Sato, D., Iguchi, K., Baba, Y. and Yamashiro, K. (2020) Menstrual Cycle Modulates Motor Learning and Memory Consolidation in Humans. Brain Sciences , 10, Article 696. https://doi.org/10.3390/brainsci10100696
Paul, J. (2022) Cycle Sync Your Business. Instagram. https://www.instagram.com/p/Cei3V0xjR61/
Cait (2023) How to Use Your Menstrual Cycle to Access Your Creative Genius. https://www.tiktok.com/@consciouslycait/video/7225248288289721627?is_from_webapp=1&sender_device=pc&web_id=7212383803213366786
Bomb, V. (2023) Cycle Syncing 101. Instagram. https://www.instagram.com/p/CnhHVQOKXqM/
Hyge Studio (2020) Find Your Flow. https://hyggestudio.yoga/online-course/
Reed, B.G. and Carr, B.R. (2018) The Normal Menstrual Cycle and the Control of Ovulation. In: Feingold, K.R., et al ., Eds., Endotext , MDText.com, Inc.
Shepard, R.N. and Metzler, J. (1971) Mental Rotation of Three-Dimensional Objects. Science , 171, 701-703. https://doi.org/10.1126/science.171.3972.701
Miller, G.A. (1956) The Magical Number Seven, Plus or Minus Two: Some Limits on Our Capacity for Processing Information. Psychological Review , 63, 81-97.
Milikowski, M. and Elshout, J.J. (1995) What Makes a Number Easy to Remember? British Journal of Psychology , 86, 537-547. https://doi.org/10.1111/j.2044-8295.1995.tb02571.x
Genzel, L., Kiefer, T., Renner, L., Wehrle, R., Kluge, M., Grözinger, M., et al . (2012) Sex and Modulatory Menstrual Cycle Effects on Sleep Related Memory Consolidation. Psychoneuroendocrinology , 37, 987-998. https://doi.org/10.1016/j.psyneuen.2011.11.006
Ertman, N., Andreano, J.M. and Cahill, L. (2011) Progesterone at Encoding Predicts Subsequent Emotional Memory. Learning & Memory , 18, 759-763. https://doi.org/10.1101/lm.023267.111
ArÃlin, K., Mueller, K., Barth, C., Rekkas, P.V., Kratzsch, J., Burmann, I., et al . (2015) Progesterone Mediates Brain Functional Connectivity Changes during the Menstrual Cycleâ—A Pilot Resting State MRI Study. Frontiers in Neuroscience , 9, Article 44. https://doi.org/10.3389/fnins.2015.00044
Roozbehi, A., Sharafi, M.T., Karimi, F. and Kamali, A.M. (2017) The Impact of Using Different Doses of Progesterone on Memory Performance. Bratislava Medical Journal , 118, 405-407. https://doi.org/10.4149/bll_2017_079
Tanabe, F., Miyasaka, N., Kubota, T. and Aso, T. (2004) Estrogen and Progesterone Improve Scopolamine-Induced Impairment of Spatial Memory. Journal of Medical and Dental Sciences , 51, 89-98.
Pompili, A., Tomaz, C., Arnone, B., Tavares, M.C. and Gasbarri, A. (2010) Working and Reference Memory across the Estrous Cycle of Rat: A Long-Term Study in Gonadally Intact Females. Behavioral Brain Research , 213, 10-18. https://doi.org/10.1016/j.bbr.2010.04.018
Luine, V.N., Jacome, L.F. and MacLusky, N.J. (2003) Rapid Enhancement of Visual and Place Memory by Estrogens in Rats. Endocrinology , 144, 2836-2844. https://doi.org/10.1210/en.2003-0004
Schoofs, D., Preuß, D. and Wolf, O.T. (2008) Psychosocial Stress Induces Working Memory Impairments in an N-Back Paradigm. Psychoneuroendocrinology , 33, 643-653. https://doi.org/10.1016/j.psyneuen.2008.02.004
Mihalj, M., Drenjančević, I., Včev, A., Šumanovac, A., Čavka, A., Vladetić, M. and Gmajnić, R. (2014) Basic Cognitive Functions across the Menstrual Cycle in a Controlled Female Cohort. Medicinski Glasnik , 11, 177-185.
Sundström-Poromaa, I. (2018) The Menstrual Cycle Influences Emotion but Has Limited Effect on Cognitive Function. In: Vitamins and Hormones , Elsevier, 349-376. https://doi.org/10.1016/bs.vh.2018.01.016
Hausmann, M., Slabbekoorn, D., Van Goozen, S.H.M., Cohen-Kettenis, P.T. and Güntürkün, O. (2000) Sex Hormones Affect Spatial Abilities during the Menstrual Cycle. Behavioral Neuroscience , 114, 1245-1250. https://doi.org/10.1037/0735-7044.114.6.1245
Scheuringer, A. and Pletzer, B. (2017) Sex Differences and Menstrual Cycle Dependent Changes in Cognitive Strategies during Spatial Navigation and Verbal Fluency. Frontiers in Psychology , 8, Article 381. https://doi.org/10.3389/fpsyg.2017.00381
Hussain, D., Hanafi, S., Konishi, K., Brake, W.G. and Bohbot, V.D. (2016) Modulation of Spatial and Response Strategies by Phase of the Menstrual Cycle in Women Tested in a Virtual Navigation Task. Psychoneuroendocrinology , 70, 108-117. https://doi.org/10.1016/j.psyneuen.2016.05.008
Ronca, F., Blodgett, J.M., Bruinvels, G., Lowery, M., Raviraj, M., Sandhar, G., et al . (2024) Attentional, Anticipatory and Spatial Cognition Fluctuate Throughout the Menstrual Cycle: Potential Implications for Female Sport. Neuropsycholog i a , 14, Article 108909. https://doi.org/10.1016/j.neuropsychologia.2024.108909
Pilarczyk, J., Schwertner, E., Wołoszyn, K. and Kuniecki, M. (2019) Phase of the Menstrual Cycle Affects Engagement of Attention with Emotional Images. Psychoneuroendocrinology , 104, 25-32. https://doi.org/10.1016/j.psyneuen.2019.02.009
Beaudoin, J. and Marrocco, R. (2005) Attentional Validity Effect across the Human Menstrual Cycle Varies with Basal Temperature Changes. Behavioural Brain Research , 158, 23-29. https://doi.org/10.1016/j.bbr.2004.08.005
Brooks-Gunn, J. and Ruble, D.N. (1982) The Development of Menstrual-Related Beliefs and Behaviors during Early Adolescence. Child Development , 53, Article 1567. https://doi.org/10.2307/1130085