Investigating connectional characteristics of Motor Cortex network
- 1 School of Life Science and Bioengineering.
- 2 School of Electronic Information and Control Engineering, Beijing University of Technology
Abstract
To understand the connectivity of cerebral cor-tex, especially the spatial and temporal pattern of movement, functional magnetic resonance imaging (fMRI) during subjects performing finger key presses was used to extract functional networks and then investigated their character-istics. Motor cortex networks were constructed with activation areas obtained with statistical analysis as vertexes and correlation coefficients of fMRI time series as linking strength. The equivalent non-motor cortex networks were constructed with certain distance rules. The graphic and dynamical measures of motor cor-tex networks and non-motor cortex networks were calculated, which shows the motor cortex networks are more compact, having higher sta-tistical independence and integration than the non-motor cortex networks. It indicates the motor cortex networks are more appropriate for information diffusion.
- V. M. Eguíluz, D. R. Chialvo, G. A. Cecchi et al. (2005) Scale-Free Brain Functional Networks. Physical Review Letters, 14 January: 018102-1~018102-4.
- A. Riecker, D. Wildgruber, K. Mathiak et al. (2003) Parametric analysis of rate-dependent hemodynamic response functions of cortical and subcortical brain structures during auditorily cued finger tapping: a fMRI study. NeuroImage, 18: 731-739.
- J. C. Zhuang, S. LaConte, S. Peltier, et al. (2005) Connectivity exploration with structural equation modeling: an fMRI study of bimanual motor coordination. NeuroImage, 25 (2): 462-470.
- K. J. Friston, (2003) Dynamic causal modeling. NeuroImage, 19: 1273-1302.
- L. Harrison, W. D. Penny, K. J. Friston, (2003) Multivariateautore-gressive modelling of fMRI time series. NeuroImage, 19: 1477–1491.
- M. Eichler, (2005) A graphical approach for evaluating effective connectivity in neural systems. Philos. Trans. R. Soc. B, 360: 953-967.
- S. Yang, D. Knoke. (2001) Optimal connections: strength and distance in valued graphs. Social Networks, 23: 285-295.
- K. E. Stephan, C. C. Hilgetag, G. A. P. C. Burns et al. (2000) Computational analysis of functional connectivity between areas of primate cerebral cortex. Phil. Trans. R. Soc. Lond. B, 355, 111-126.
- D. J. Felleman & D. C. Van Essen, (1991) Distributed hierar-chical processing in the primate cerebral cortex. Cereb Cortex, 1: 1-47.
- S. Dodel, J. M. Herrmann, T. Geisel. (2002) Functional connec-tivity by cross-correlation clustering. Neurocomputing, 44- 46:1065-1070.
- S. G. Tononi and G. M. Edelman. (2000) Theoretcal Neuro-anatomy: Relating Anatomical and Functional Connectivity in Graphs and Cortical Connection Matrices, Cerebral Cortex, 10: 127-141.
- http://www.fmridc.org.
- K. Y. Haaland, C. e L. Elsinger et al. (2004) Motor Sequence Complexity and Performing Hand Produce Differential Patterns of Hemispheric Lateralization. Journal of Cognitive Neurosci-ence, 16(4): 621-636.
- http://www. analytictech.com.
- A. McNamara, M. Tegenthoff, H. Dinse, et al. Increased func-tional connectivity is crucial for learning novel muscle synergies. Neuroimage, 2007, 35: 1211-1218 (p1213, ROI= 6mm, 7voxels).
- http://www.talairach.org.