Mesenchymal stem cells for the treatment of tendon disorders — Oak Academic Publishing
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Mesenchymal stem cells for the treatment of tendon disorders
Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic
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Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
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Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
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Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
1 Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic
2 Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
3 Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
4 Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic Department of Neuroscience, Second Faculty of Medicine, Charles University, Prague, Czech Republic
Tendon disorders are associated with increased morbidity and a reduction in the quality of life, especially in people of working age. Recently, a new approach, cell-based therapy, offers promising potential to treat tendon injuries. Mesenchymal stem cells are the most suitable candidates for such therapies due to their capacity to differentiate into cells of mesodermal origin, their paracrine properties and their potential use in autologous transplantation. This review summarizes experimental as well as clinical data focusing on the use of mesenchymal stem cells to treat tendinophaties.
KeywordsTendinophatyTendinosisTendonitisModels of Tendon InjuriesMesenchymal Stem CellsRotator CuffAchilles TendonTendon Rupture
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