Acellular Amniotic Membrane Patch Regeneration for Burn Injury: The Future for Wound Healing
- 1 School of Health Sciences, Positivo University, Curitiba, Brazil
- 2 School of Health Sciences, Positivo University, Curitiba, Brazil
- 3 School of Health Sciences, Positivo University, Curitiba, Brazil
- 4 School of Health Sciences, Positivo University, Curitiba, Brazil
- 5 School of Health Sciences, Positivo University, Curitiba, Brazil
- 6 The Paraná Institute of Technology, Curitiba, Brazil
- 7 School of Health Sciences, Positivo University, Curitiba, Brazil
- 8 Gel Lab, Michigan State University, East Lansing, USA
- 9 School of Health Sciences, Positivo University, Curitiba, Brazil
- 10 School of Health Sciences, Positivo University, Curitiba, Brazil
- 11 School of Medical Sciences, Pontifical Catholic University of Paraná, Curitiba, Brazil
- 12 School of Health Sciences, Positivo University, Curitiba, Brazil
- 13 School of Health Sciences, Positivo University, Curitiba, Brazil
Abstract
Acellular amniotic membrane (AAM) is a biodegradable and biocompatible natural that has a wide range of applications in the field of pharmaceutics, biomedical, chemical and cosmetics industry. One of the most interesting characteristics of AAM is its antibacterial and anti-inflammatory, anti-angiogenic, anti-fibrosis activity is an attractive approach for treating inflammatory disorders, wounds, and burns. The isolated use of AAM may not be sufficient to produce an adequate anti-inflammatory and antimicrobial effect to fulfill different purposes, has attracted considerable attention that has similar properties to the native tissues. This mini-review offers a focuses on modern aspects of the biomaterials, growth factors, biocompatibility, and acellular matrix which are the basic elements for use in the tissue regeneration and replacement after an injury.
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