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A Novel Antibacterial Dental Resin Composite

¹ Department of Biomedical Engineering, Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, USA
² Department of Biomedical Engineering, Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, USA
³ Department of Biomedical Engineering, Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, USA
⁴ Department of Oral Biology, School of Dentistry, Indiana University Indianapolis, USA
⁵ Department of Oral Biology, School of Dentistry, Indiana University Indianapolis, USA
⁶ Department of Biomedical Engineering, Purdue School of Engineering and Technology Indiana University-Purdue University at Indianapolis, Indianapolis, USA

Journal of Biomaterials and Nanobiotechnology·Volume 03 (2012)·Pages 130–135·Published 28 April 2012·DOI10.4236/jbnb.2012.32018

Abstract

This study reports the synthesis and evaluation of a novel furanone-containing antibacterial resin composite. Compres-sive strength (CS) and S. mutans viability were used to evaluate the mechanical strength and antibacterial activity of the composites. With 5% to 30% addition of the furanone derivative, the composite showed no change in CS but a significant antibacterial activity with a 16% - 68% reduction in the S. mutans viability. Further, the antibacterial activity of the modified composite was not affected by human saliva. The aging study implies that the modified composite may have a long-lasting antibacterial function. Within the limitations of this study, it appears that this experimental resin composite may potentially be developed into a clinically attractive dental restorative due to its high mechanical strength and antibacterial function.

KeywordsFuranone DerivativeAntibacterialResin CompositeCS&lti&gtS. mutans&lt/i&gtViability

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A Novel Antibacterial Dental Resin Composite

Abstract

References (27)