Synthesis of Biphasic Calcium Phosphate by Hydrothermal Route and Conversion to Porous Sintered Scaffold
- 1 School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Penang, Malaysia;
- 2 School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Penang, Malaysia;
- 3 School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Penang, Malaysia;
- 4 School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Penang, Malaysia;
- 5 Department of Biomedical Sciences and Technology, Faculty of Dentistry, Universitas Gadjah Mada, Yogyakarta, Indonesia;
- 6 Department of Biomaterials, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.
Abstract
Biphasic calcium phosphate (BCP) consisting of hydroxyapatite (HA) and β -tricalcium phosphate ( β -TCP) was suc cessfully synthesized by new hydrothermal route using β -TCP as precursor. The X-ray diffraction analysis of as-syn thesized powder indicated that β -TCP had been transformed into HA phase and amount of HA formed gradually in creased with prolonged time. The results revealed that the recent technique may be able to control the composition of the obtained BCP which would influence the bioresorbability. Porous body of BCP was prepared by impregnation of polymeric sponge template with the slurry of the powder followed by sintering. The X-ray diffraction of porous product revealed that the composition of β -TCP increased after sintering indicating that HA had been decomposed. Porous BCP obtained from the recent technique possessed both macro and micropores structure which are useful for rapid tissue formation. Besides, the recent porous fabrication technique yielded porous BCP which preserved the sponge template morphology, enabling it to fabricate porous material with controlled pores structure.
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