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Comparative Study of Synergistic Effects of Antibiotics with Triangular Shaped Silver Nanoparticles, Synthesized Using UV-Light Irradiation, on <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>
Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
- 1 Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
- 2 Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
- 3 Department of Physics, Maulana Azad National Institute of Technology (M.A.N.I.T.), Bhopal, India
Journal of Biomaterials and Nanobiotechnology·Volume 05 (2014)·Pages 186–193·Published 5 June 2014·DOI10.4236/jbnb.2014.53022
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Abstract
In the present work, a comparative study of antibacterial activity and synergistic effects of triangular silver nanoparticles in combination with two standard antibiotics is discussed for Staphylococcus aureus and Pseudomonas aeruginosa . A green route was developed to synthesise silver nanoparticles in which silver oxalate was taken as precursor, black tea leaves extract as surfactant and chitin as a stabilizing agent. A grey coloured colloidal solution of silver nanoparticles was obtained which was characterized by using various techniques like X-ray diffractometer (XRD), transmission electron microscopy (TEM) and UV-visible spectroscopy. Anti-bacterial studies gave approximately equal inhibition zones for both the combinations which states that silver nanoparticles are to be equally effective and synergistic effects were clearly observed in case of P. aeruginosa .
KeywordsTriangular Silver NanoparticleBlack Tea Leaves ExtractUV-Irradiation<i>Staphylococcus aureus</i><i>Pseudomonas aeruginosa</i>Ampicillin and Gentamycin
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