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Crystal structure of PqqB from <i>Pseudomonas putida</i> at 2.2 Å resolution
Department of Molecular Biology, University of Salzburg, Salzburg, Austria
Department of Molecular Biology, University of Salzburg, Salzburg, Austria
Department of Molecular Biology, University of Salzburg, Salzburg, Austria
- 1 Department of Molecular Biology, University of Salzburg, Salzburg, Austria
- 2 Department of Molecular Biology, University of Salzburg, Salzburg, Austria
- 3 Department of Molecular Biology, University of Salzburg, Salzburg, Austria
Journal of Biophysical Chemistry·Volume 03 (2012)·Pages 206–210·Published 29 May 2012·DOI10.4236/jbpc.2012.32023
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Abstract
Pyrroloquinoline quinone (PQQ) is an important redox-active cofactor for many bacterial dehy-drogenases. It's biosynthetic pathway involves six or seven genes, one of which is pqqB. Former studies indicated that the protein encoded by pqqB, namely PqqB, functions as a PQQ transporter. Here we report the crystal structure of PqqB from Pseudomonas putida at 2.2 ? resolution together with functional studies to verify this theory.
KeywordsPqqBPQQBiosynthetic PathwayX-Ray Crystallography
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