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Pilot Study into Super-Fractionation Treatment Strategy of Acne and Rosacea
Derma-Clinic, Karlsruhe, Germany
Wellcomet GmbH, Karlsruhe, Germany
- 1 Derma-Clinic, Karlsruhe, Germany
- 2 Wellcomet GmbH, Karlsruhe, Germany
Journal of Cosmetics, Dermatological Sciences and Applications·Volume 03 (2013)·Pages 197–202·Published 15 August 2013·DOI10.4236/jcdsa.2013.33030
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Abstract
It is evident that matrix metalloproteinases (MMPs) are involved in the pathophysiology of different inflammatory skin diseases. In this pilot study, we investigated the ability of very high frequency ultrasound — frequencies of approxima tely 10 MHz — to modulate the activity of MMPs in the skin in inflammatory skin diseases such as acne and rosacea. It was shown that such waves can significantly improve the skin appearance in these diseases; however, the results are dependent on applied treatment schedule. The best results were obtained through the application of a super-fractionation strategy in the form of home treatments carried out twice daily.
KeywordsPilot StudyAcneRosaceaSuper-FractionationHome Treatment
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