Study on the Repairing Effect of Cosmetics Containing <i>Artemisia annua</i> on Sensitive Skin
- 1 R & D Center, Yinsha Cosmetics Co., Ltd., Chengdu, China
- 2 R & D Center, Yinsha Cosmetics Co., Ltd., Chengdu, China
- 3 Institute of Medicinal Fungi, Sichuan Academy of Chinese Medicine Science, Chengdu, China
Abstract
In view of the increasing sensitivity of consumer skin in recent years, cosmetics containing Artemisia annua extract was tested to evaluate its effectiveness in repairing sensitive skin. Through the experiment of xylene-induced ear swelling in mice, it was found that the inhibition rates of ear swelling in mice induced by xylene in three groups of cosmetics containing Artemisia annua extract reached 60.40%, 73.36% and 74.01%, respectively, close to the positive drug group. Twenty-five sensitive skin volunteers were selected for human clinical trial, and the skin TEWL value, cuticle hydration degree and skin heme (ultra-high concentration) were tested. The results showed that using cosmetics containing Artemisia annua extract for four weeks could effectively increase the hydration degree of cheek cuticle by 63.90% and reduce transepidermal waterloss (TEWL) by 21.51%. The skin heme (ultra-high concentration) decreased by 69.14% and the affected area decreased by 77.47%. The results show that the cosmetics containing Artemisia annua extract can inhibit inflammation, repair skin barrier, improve damaged skin, and reduce redness and other sensitive skin symptoms.
- Willis, C.M., Shaw, S., De Lacharrieáre, O., et al. (2001) Sensitive Skin: An Epidemiological Study. British Journal of Dermatology, 145, 258-263. https://doi.org/10.1046/j.1365-2133.2001.04343.x
- Fan, L., Jia, Y., Cui, L., et al. (2018) Analysis of Sensitive Skin Barrier Function: Basic Indicators and Sebum Composition. International Journal of Cosmetic Science, 40, 117-126. https://doi.org/10.1111/ics.12442
- Smith, C. (2016) Factors When Formulating for Sensitive Skin. Personal Care, 4, 18-20.
- He, L., Zheng, J., Ma, H.Q., et al. (2017) Expert Consensus on Diagnosis and Treatment of Sensitive Skin in China. The Chinese Journal of Dermatovenereology, No. 1, 1-4.
- Beradesca, E., Farage, M. and Maibach, H. (2013) Sensitive Skin: An Overview. International Journal of Cosmetic Science, 35, 2-8. https://doi.org/10.1111/j.1468-2494.2012.00754.x
- Roussaki-Schulze, A.V., Zafiriou, E., Nikoulis, D., et al. (2005) Objective Biophysical Findings in Patients with Sensitive Skin. Drugs under Experimental and Clinical Research, 31, 17-24.
- Maibach, H.I., Lammintausta, K., Berardesca, E., et al. (1989) Tendency to Irritation: Sensitive Skin. Journal of the American Academy of Dermatology, 21, 833-835. https://doi.org/10.1016/S0190-9622(89)70259-0
- Agner, T. and Serup, J. (1989) Quantification of the DMSO-Response—A Test for Assessment of Sensitive Skin. Clinical and Experimental Dermatology, 14, 214-217. https://doi.org/10.1111/j.1365-2230.1989.tb00935.x
- An, S., Lee, E., Kin, S., et al. (2007) Comparison and Correlation between Stinging Responses to Lactic Acid and Bioengineering Parameters. Contact Dermatitis, 57, 158-162. https://doi.org/10.1111/j.1600-0536.2007.01182.x
- Wu, Y.Y. and Wang, X.M. (2003) Test and Evaluation of Sensitive Skin. Chinese Journal of Medical Aesthetics and Cosmetology, No. 4, 249-251.
- Chapis, M. (2018) Weak and Damaged Skin Repaired by Maracuja. Personal Care Europe, No. 2, 43-48.
- Golenser, J., Waknine, J.H., Krugliak, M., et al. (2006) Current Perspectives on the Mechanism of Action of Artemisinins. International Journal for Parasitology, 36, 1427-1441. https://doi.org/10.1016/j.ijpara.2006.07.011
- Yang, D.M. and Liew, F.Y. (1993) Effects of Qinghaosu (Artemisinin) and Its Derivatives on Experimental Cutaneous Leishmaniasis. Parasitology, 106, 7-11. https://doi.org/10.1017/S0031182000074758