Epidemiological and Histopathological Aspect of Precancerous and Cancerous Lesions of the Cervix in the Health District of Commune 5 of Bamako, the CHU of Point “G” and the Gabriel Touré University Hospital of Bamako in Mali
- 1 Faculty of Medicine and Odontostomatology, University of Science and Technology, Bamako, Mali
- 2 Department of Gynecology and Obstetrics, Reference Health Centre of Commune V, Bamako, Mali
- 3 Department of Obstetrics and Gynecology, Koutiala Reference Health Centre, Sikasso, Mali
- 4 Department of Gynecology and Obstetrics, Reference Health Centre of Commune V, Bamako, Mali
- 5 Department of Gynecology and Obstetrics, Gabriel Touré University Hospital, Bamako, Mali
- 6 Department of Gynecology and Obstetrics, Reference Health Centre of Commune V, Bamako, Mali
- 7 Faculty of Medicine and Odontostomatology, University of Science and Technology, Bamako, Mali
- 8 Department of Gynecology and Obstetrics, Reference Health Centre of Commune V, Bamako, Mali
- 9 Faculty of Medicine and Odontostomatology, University of Science and Technology, Bamako, Mali
- 10 Department of Gynecology and Obstetrics, Reference Health Centre of Commune V, Bamako, Mali
- 11 Faculty of Medicine and Odontostomatology, University of Science and Technology, Bamako, Mali
- 12 Faculty of Medicine and Odontostomatology, University of Science and Technology, Bamako, Mali
Abstract
Objective: The aim was to take stock of the screening and treatment of precancerous and cancerous lesions of the cervix in the health district of commune V of Bamako, the “ G ” point and the Gabriel Touré University Hospital in Bamako, Mali. Patients and Methods: This was a descriptive, cross-sectional , analytical study with retrospective and prospective data collection over an 8-year period from January 1, 2010 to December 31, 2017. This was a multi-center study. Results: From January 1, 2010 to December 31, 2017, 42 , 492 women were screened, representing a frequency of 24.30%. The median age of the women screened was 32 years; 25% were under the age of 25. Three-fourth of the women screened was in the 20 - 49 age group. Of the 22 , 842 women screened , 90.1% of them had a normal col to IVA/IVL. However , 4.1% of cervical positivity had with acetic acid and 5.1% of positivity to Lugol. 0.7% of the women screened clinically had cancerous lesions. Histologically, 96.5% of the women screened had a normal cervix with benign lesions. For pathological histological findings, we noted 2.6% of precancerous lesions and 0.8% of squamous cell carcinomas and 0.1% of adenocarcinoma. Conclusion: Improved screening indicators with IVA/IV reduce the rate of morbidity and mortality from cervical cancer.
- Arbyn, M., Raifu, A.O., Autier, P., et al. (2007) Burden of Cervical Cancer in Europe: Estimates for 2004. Annals of Oncology, 18, 1708-1715. https://doi.org/10.1093/annonc/mdm079
- Autier, P., Coibion, M., Huet, F., et al. (1996) Transformation Zone Location and Intra Epithelial Neoplasia of the Cervix Uteri. British Journal of Cancer, 74, 488-490. https://doi.org/10.1038/bjc.1996.388
- Basu, P.S., Sankaranarayanan, R., Mandal, R., et al. (2003) Visual Inspection with Aceticacid and Cytology in the Early Detection of Cervical Neoplasia in Kolkata, India. International Journal of Gynecological Cancer, 13, 626-632. https://doi.org/10.1136/ijgc-00009577-200309000-00009
- Belinson, J.L., Pretorius, R.G., Zhang, W.H., et al. (2001) Cervical Cancer Screening by Simple Visual Inspection after Acetic Acid. Obstetrics & Gynecology, 98, 441-444. https://doi.org/10.1097/00006250-200109000-00014
- Anderson, G.H., Boyes, D.A., Benedet, J.L., et al. (1988) Organisation and Results of the Cervical Cytology Screening Programme in British Columbia, 1955-85. British Medical Journal (Clinical Research Ed.), 296, 975-978. https://doi.org/10.1136/bmj.296.6627.975
- Denny, L., Quinn, M. and Sankaranarayanan, R. (2006) Chapter 8: Screening for Cervical Cancer in Developing Countries. Vaccine, 24, S3/71-7. https://doi.org/10.1016/j.vaccine.2006.05.121
- Smith, J. and Parkin, D.M. (2000) Evaluation and Monitoring of Cancer Screening. European commission, Brussels-Luxemburg.
- Sankaranarayanan, R., Budukh, A.M. and Rajkumar, R. (2001) Effective Screening Programmes for Cervical Cancer in Low- and Middle-Income Developing Countries. Bulletin of the World Health Organization, 79, 954-962.
- Hakama, M. (1997) Screening for Cervical Cancer: Experience of the Nordic Countries. In: Franco, E. and Monsonego, J., Eds., New Developments in Cervical Cancer Screening and Prevention, Blackwell Science, Oxford.
- Irwin, K.L., Oberle, M.W. and Rosero-Bixby, L. (1991) Screening Practices for Cervical and Breast Cancer in Costa Rica. Bulletin of the Pan American Health Organization, 25, 16-26.
- Sankaranarayanan, R. and Pisani, A.P. (1997) Prevention Measures in the Third World: Are They Practical. In: New Developments in Cervical Cancer Screening and Prevention, Blackwell Science, Oxford.
- Chumworathayi, B., Limpaphayom, K., Srisupundit, S., et al. (2006) VIA and Cryotherapy: Doing What’s Best. Journal of the Medical Association of Thailand, 89, 1333-1339.