Delivered Dose Verification for Lung Cancer Stereotactic Body Radiotherapy Using Cone-Beam CT
- 1 Department of Radiation Oncology, Hunan Academy of Traditional Chinese Medicine Affiliated Hospital, Changsha, China
- 2 School of Medical Information and Engineering, Guangdong Pharmaceutical University, Guangzhou, China
- 3 Guangdong Province Precise Medicine and Big Data Engineering Technology Research Center for Traditional Chinese Medicine, Guangzhou, China
- 4 Department of Radiation Oncology, Yunnan Tumor Hospital, The Third Affiliated Hospital of Kunming Medical University, Kunming, China
- 5 The Second Af?liated Hospital of Hainan Medical University, Haikou, China
- 6 Department of Radiation Oncology, School of Medicine, Xiang’an Hospital of Xiamen University, Xiamen University, Xiamen, China
- 7 Department of Radiation Oncology, School of Medicine, Xiang’an Hospital of Xiamen University, Xiamen University, Xiamen, China
- 8 Department of Radiation Oncology, School of Medicine, Xiang’an Hospital of Xiamen University, Xiamen University, Xiamen, China
Abstract
Purpose: Verified the delivered dose distribution of lung cancer Stereotactic Body Radiotherapy (SBRT) using the cone-beam CT images. Methods: Twenty lung cancer patients who underwent SBRT with 100 CBCT images were enrolled in this study. Delivered dose distributions were recalculated on CBCT images with the deformed and non-deformed metho d s , respectively. The planned and delivered dose distributions were compared using the dose-volume histograms. Results: The delivered target coverage (V100) per patient inside target volume deviated on average were 0.83% ± 0.86% and 1.38% ± 1.40% for Pct vs . Pcbct and Pct vs . Pdcbct, respectively. The Conformity Index (CI) and Gradient Index (GI) showed a good agreement among the plans. For the critical organs, only minor differences were observed between the planned dose and the delivered dose. Conclusions: CBCT images were a useful tool for setup and dose deliver y verification for lung cancer patients who underwent SBRT.
- Fakiris, A.J., McGarry, R.C., Yiannoutsos, C.T., Papiez, L., Williams, M., Henderson, M.A. and Timmerman, R. (2009) Stereotactic Body Radiation Therapy for Early-Stage Non-Small-Cell Lung Carcinoma: Four-Year Results of a Prospective Phase II Study. International Journal of Radiation Oncology.Biology.Physics, 75, 677-682. https://doi.org/10.1016/j.ijrobp.2008.11.042
- Guckenberger, M., Wilbert, J., Krieger, T., Richter, A., Baier, K., Meyer, J. and Flentje, M. (2007) Four-Dimensional Treatment Planning for Stereotactic Body Radiotherapy. International Journal of Radiation Oncology.Biology.Physics, 69, 276-285. https://doi.org/10.1016/j.ijrobp.2007.04.074
- Joyner, M., Salter, B.J., Papanikolaou, N. and Fuss, M. (2006) Stereotactic Body Radiation Therapy for Centrally Located Lung Lesions. Acta Oncologica, 45, 802-807. https://doi.org/10.1080/02841860600915322
- Nagata, Y., Negoro, Y., Aoki, T., Mizowaki, T., Takayama, K., Kokubo, M., et al. (2002) Clinical Outcomes of 3D Conformal Hypofractionated Single High-Dose Radiotherapy for One or Two Lung Tumors Using a Stereotactic Body Frame. International Journal of Radiation Oncology.Biology.Physics, 52, 1041-1046. https://doi.org/10.1016/S0360-3016(01)02731-6
- Okunieff, P., Petersen, A.L., Philip, A., Milano, M.T., Katz, A.W., Boros, L., Schell, M.C. (2006) Stereotactic Body Radiation Therapy (SBRT) for Lung Metastases. Acta Oncologica, 45, 808-817. https://doi.org/10.1080/02841860600908954
- Onishi, H., Araki, T., Shirato, H., Nagata, Y., Hiraoka, M., Gomi, K., et al. (2004) Stereotactic Hypofractionated High-Dose Irradiation for Stage I Nonsmall Cell Lung Carcinoma: Clinical Outcomes in 245 Subjects in a Japanese Multiinstitutional Study. Cancer, 101, 1623-1631. https://doi.org/10.1002/cncr.20539
- Knöös, T., Wieslander, E., Cozzi, L., Brink, C., Fogliata, A., Albers, D., Nyström, H. and Lassen, S. (2006) Comparison of Dose Calculation Algorithms for Treatment Planning in External Photon Beam Therapy for Clinical Situations. Physics in Medicine & Biology, 51, 5785-5807. https://doi.org/10.1088/0031-9155/51/22/005
- Papanikolaou, N., Battista, J., Boyer, A., Klein, E. and Sharpe, M. (2004) Tissue Inhomogeneity Corrections for Megavoltage Photon Beams. AAPM Report 85, Task Group No. 65 of the Radiation Therapy Committee of the American Association of Physicists in Medicine, Medical Physics Publishing, Madison.
- Bissonnette, J.P., Purdie, T.G., Higgins, J.A., Li, W. and Bezjak, A. (2009) Cone-Beam Computed Tomographic Image Guidance for Lung Cancer Radiation Therapy. International Journal of Radiation Oncology.Biology.Physics, 73, 927-934. https://doi.org/10.1016/j.ijrobp.2008.08.059