Research ArticleOpen AccessGoogle Scholar indexed
Recurrent Dermatofibrosarcoma Protuberant of the Hand: A Case Report
Department of Oncology, University Hospital Tanambao, Antsiranana, Madagascar
Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
Department of Anatomy Pathology, Institut Pasteur of Madagascar, Antananarivo, Madagascar
Department of Traumatology and Orthopedics, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
- 1 Department of Oncology, University Hospital Tanambao, Antsiranana, Madagascar
- 2 Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
- 3 Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
- 4 Department of Anatomy Pathology, Institut Pasteur of Madagascar, Antananarivo, Madagascar
- 5 Department of Traumatology and Orthopedics, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
- 6 Department of Radiotherapy, University Hospital Joseph Ravoahangy Andrianavalona, Antananarivo, Madagascar
Journal of Cancer Therapy·Volume 13 (2022)·Pages 425–429·Published 30 June 2022·DOI10.4236/jct.2022.137037
Copy link · social · email
Abstract
Dermatofibrosarcoma is a rare, slow growing tumor with a tendency to local recurrence. The treatment is mainly surgical. In Madagascar there is no specialized center for the management of soft tissue sarcomas. It is in this context that we report a case of a 45-year-old man, driver, presenting with recurrent dermatofibrosarcoma of the left hand. The diagnosis was confirmed by the positivity of the CD34 marker. Extensive local excision surgery was performed with the patient’s consent. After free years of treatment, there is no tumor recurrence.
KeywordsDermatofibrosarcomaHandWide SurgeryRecurrence
- Hao, X., Billings, S., Wu, F., Stultz, T., Procop, G., Mirkin, G., et al. (2020) Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment. Journal of Clinical Medicine, 9, Article No. 1752. https://doi.org/10.3390/jcm9061752
- Shah, K.K., McHugh, J., Folpe, A. and Patel, R. (2018) Dermatofibrosarcoma Protuberans of Distal Extremities and Acral Sites: A Clinicopathologic Analysis of 27 Cases. The American Journal of Surgical Pathology, 42, 413-419. https://doi.org/10.1097/PAS.0000000000000998
- Lyu, A. and Wang, Q. (2018) Dermatofibrosarcoma Protuberans: A Clinical Analysis. Oncology Letters, 16, 1855-1862. https://doi.org/10.3892/ol.2018.8802
- Chiang, K.T., Lee, S.Y. and Chu, H. (2015) Dermatofibrosarcoma Protuberans, a Rare But Locally Aggressive Tumor on Finger: Clinical and Aeromedical Considerations. Case Reports in Plastic Surgery and Hand Surgery, 2, 15-18. https://doi.org/10.3109/23320885.2014.995185
- Li, Y., Wang, C., Xiang, B., Chen, S., Li, L. and Ji, Y. (2017) Clinical Features, Pathological Findings and Treatment of Recurrent Dermatofibrosarcoma Protuberans. Journal of Cancer, 8, 1319-1323. https://doi.org/10.7150/jca.17988
- Li, Y., Wang, C., Xiang, B., Chen, S., Li, L. and Ji, J. (2017) Clinical Features, Pathological Findings and Treatment of Recurrent Dermatofibrosarcoma Protuberans. Journal of Cancer, 8, 1319-1323. https://doi.org/10.7150/jca.17988.
- Stranahan, D., Cherpelis, B.S., Glass, L.F., Ladd, S. and Fenske, N.A. (2009) Taches immunohistochimiques dans la chirurgie de Mohs: Une revue. Dermatologic Surgery, 35, 1023-1034. https://doi.org/10.1111/j.1524-4725.2009.01179.x
- Pedeutour, F., Simon, M.P., Minoletti, F., Barcelo, G., Terrier-Lacombe, M.J., Combemale, P., et al. (1996) Translocation, t(17;22)(q22;q13), in Dermatofibrosarcoma Protuberans: A New Tumor-Associated Chromosome Rearrangement. Cytogenetic and Genome Research, 72, 171-174. https://doi.org/10.1159/000134178
- Navarrete-Dechent, C., Mori, S., Barker, C.A., Dickson, M.A. and Nehal, K.S. (2019) Imatinib Treatment for Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans: A Systematic Review. JAMA Dermatology, 155, 361-369. https://doi.org/10.1001/jamadermatol.2018.4940
- Malan, M., Xuejingzi, W. and Quan, S.J. (2019) The Efficacy of Mohs Micrographic Surgery over the Traditional Wide Local Excision Surgery in the Cure of Dermatofibrosarcoma Protuberans. The Pan African Medical Journal, 33, Article No. 297. https://doi.org/10.11604/pamj.2019.33.297.17692