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Treatment Results of Adjuvant Brachytherapy as Monotherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University
The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Faculty of Medicine, Christian-Albretch University, Kiel, Germany
The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- 1 The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- 2 Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
- 3 Biostatistics and Applied Statistics Laboratory, Department of Statistics, Faculty of Science, Chiang Mai University, Chiang Mai, Thailand
- 4 The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- 5 The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- 6 The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
- 7 Faculty of Medicine, Christian-Albretch University, Kiel, Germany
- 8 The Division of Therapeutic Radiology and Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Journal of Cancer Therapy·Volume 06 (2014)·Pages 34–39·Published 26 December 2014·DOI10.4236/jct.2015.61005
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Abstract
Purpose: To report the retrospective study of using intravaginal brachytherapy as adjuvant monotherapy for endometrial cancer. Materials and Methods: From 2001-2009, 47 patients who received completely surgical staging for endometrial carcinoma and were designed by multidisciplinary team were enrolled. All patients received intravaginal brachytherapy (IVBT) with the dose of 5.5 - 7 Gy in 2 - 6 fractions. The treatment results and late toxicities were evaluated and recorded. Results: At the median follow-up time of 44 months, the local control, disease-free survival, metastasis-free survival and overall survival rates were 100%, 97.9%, 97.9% and, 97.9%, respectively. Only age showed the statistical significance with the p-value of 0.046. Two patients (4.3%) developed late genitourinary toxicity. Conclusion: The using of adjuvant IVBT as monotherapy for endometrial carcinoma is feasible.
KeywordsEndometrial CancerAdjuvantBrachytherapyMonotherapy
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