The aim of this paper is to review the radiological evaluation of thyroid nodules detected with ultrasonography (US), thoroughly and in harmony with the clinical-endocrinological-surgical management. In this review, we tried to summarize the radiological evaluation of nodules detected in the thyroid in compliance with recently published and accepted guidelines, including the most advanced sonographic protocols, emphasizing the indications of cross-sectional imaging when needed. In this review important aspects were demonstrated with tables, illustrations and take-home points and technical aspects were emphasized with images and diagrams. We believe that this review, which is concluded with an extensive summary with the support of most recent sources, is an up-to-date and comprehensive evaluation of the broad spectrum of thyroid nodule radiology. We think that the management of any kind of nodule that can be encountered during the US examination can be done successfully by going through the paths described in the pictures, tables and texts in this article.
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