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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Joan C. Smith, Michael W. Schäffer, Billy R. Ballard, Duane T. Smoot, Alan J. Herline, Samuel E. Adunyah, Amosy E. M’Koma
The incidence of familial adenomatous polyposis (FAP) is one in 7,000 to 12,000 live births. Virtually, all surgically untreated patients with FAP inevitably develop colorectal-cancer in their lifetime because they carry the adenomatous polyposis coli gene. T…
Muddasir Hassan Abbasi, Tasleem Akhtar, Ihtzaz A. Malik, Sana Fatima, Babar Khawar, Khawaja Abdul Mujeeb, Ghulam Mustafa, Shabir Hussain, Javaid Iqbal, Nadeem Sheikh
Background : Thioacetamide (TAA) has been used extensively in the development of suitable animal models of acute and chronic liver injury employing various doses, times and routes of its administration, particularly in drinking water due to its resemblance wi…
Inigo Martinez-Zubiaurre, Christopher G. Fenton, Hagar Taman, Ingvild Pettersen, Turid Hellevik, Ruth H. Paulssen
Cancer-associated fibroblasts (CAFs) are key elements in the progression of cancer and thereby represent important targets for cancer therapies. Increased attention has been given to ablative radiotherapy in the clinics. Therefore, in this study we have aimed…
John J. Wille, Jong Y. Park
The 5-methylationcytosine (5-MC) DNA content of murine embryonic fibroblasts arrested in G 1 by four growth conditions (Gc, Gn, Gd, and Gs) were hypermethylated relative to rapidly growing (RG) fibroblasts. Normal human keratinocytes (NHK) arrested in G 1 by…
Wenjing Xu, Zhenghua Jiang, Dongyun Huang, Muyun Zhu, Qian Huang, Hui Ge, Juan Liu, Yan Qin
Background: To those patients with advanced lung cancer, the ultimate objective is to improve the quality of life, and lung function is an important factor affecting quality of life. We detect lung function of patients with lung cancer and study the correlati…
André Buchali, Christina Schröder, Dietrich Sidow, Eyck Blank
Purpose: Investigation of the influence of radiation dose to salivary glands on xerostomia in patients with head and neck cancers. Methods: From October 2002 to December 2011, 548 patients with head and neck carcinomas were treated in our department using int…
Alexandra Kopitopoulou, Ioannis Ntanos, Muhammad W. Saif, Kostas Syrigos
Background : Overall survival (OS) and quality of life in patients with advanced non small cell lung cancer (NSCLC) remains to the day highly unsatisfactory. Better understanding of the mechanisms of oncogenesis resulted in the development of new drugs, which…
Oscar Zuñiga, Víctor H. Vázquez, Ana María Velázquez, Víctor H. Abrego, Sandra Díaz-Barriga Arceo, Patricia Ramírez, Roberto Díaz, Enrique Angeles
The balance between cell proliferation and cell growth characterizes tissue homeostasis on one side and cell death on the other side. Fas receptor-mediated apoptosis is a control mechanism for tissue homeostasis, and avoiding this death pathway predisposes to…
Fumio Yamaguchi, Takayuki Asakura, Hiroshi Takahashi, Takayuki Kitamura, Akira Teramoto
We investigated the feasibility of sonodynamic therapy for glioma by low frequency ultrasoundwith5-aminolevulinic acid (5-ALA), a precursor of protoporphyrin IX (PpIX) in heme synthetic process. In vivo tumor model was made by inoculating human glioma cell li…
Erion Dobi, Thierry Nguyen, Christophe Borg, Xavier Pivot, Bernard Royer, Stefano Kim
Background: metronomic chemotherapy is based on antiangiogenic and immunologic mechanisms obtained by the administration of traditional cytotoxic drugs at lower concentration without rest periods. The low dosage induces fewer or no side effect compared to cla…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).