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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Raef Riad, Magdy Kotb, Walid Omar, Ahmed Zaher, Emad Ebied, Alexander Gregory Pitman, Hussein Abdel Dayem
Radio-labelled MIBG therapy has been tried in the treatment of advanced stage III and IV neuroblastoma in an attempt to improve patients outcome. The use of radiolabelled MIBG to treat neuroblastoma has arisen from the high sensitivity and specificity of in v…
Jue Wang, Fenwei Wang
<b>Background:</b> The objective of this study was to evaluate the impact of radical prostatectomy on carcinosarcoma of the prostate. Methods: Patients diagnosed with carcinosarcoma of the prostate from 1977 through 2007 were identified in the Surveillance, E…
Xijian Zhou, Jun Yang, Jinying Liang, Peng Li, Yuquan Wu, Xiaoqiang Fan, Xiangyong Li
The study was designed to evaluate the therapeutic and side effects of Bevacizumab plus FOLFIRI regimen as front-line therapy for Chinese patients with advanced colorectal cancer. A total of 15 previously untreated patients with advanced colorectal cancer rec…
Xiaonan Wang, Qing Wu, Xu Yang, Liansheng Zhang, Yiping Wu, Yanwen Shu
The purpose Celastrol, the main active compound of the Celastrus genus plants, belonging to Celastraceae, has recently marked antitumour potency on solid tumours of various derivations, <b>Methods:</b> We demonstrate here that Celastrol also present powerful…
Iori Kisu, Kouji Banno, Megumi Yanokura, Yusuke Kobayashi, Arisa Ueki, Asuka Ono, Kennta Masuda, Wataru Yamagami, Hiroyuki Nomura, Akira Hirasawa, Nobuyuki Susumu, Daisuke Aoki
Atypical polypoid adenomyoma (APAM) is a rare polypoid tumor that generally occurs in women of reproductive age who have abnormal genital bleeding. The tumor was reported as a new disease concept by Mazur in 1981. Pathologically, APAM consist of irregularly p…
Carmel Nirupa Anandadas, Susan Elizabeth Davidson, Noel William Clarke, Stephen Charles William Brown, John Paul Logue, Lynne Gilmore, Richard Swindell, Gerald Nicholas Collins, Patrick Henry O’Reilly, Guy David Wemyss-Holden, Maurice Waiming Lau, Pradip Madhukar Javle, Vijay Alini Chandi Ramani, Richard James Brough, James Pinson Wylie, Richard Andrew Cowan
Objectives: In 1997, a study was launched to investigate the treatment of early prostate cancer. Using a patient preference design, health-related quality-of-life (HRQOL) and disease specific HRQOL was assessed prospectively to compare men undergoing radical…
Serap Demir, Johanna M. A. Pijnenborg, Ruud L. M. Bekkers
<b>Background and Objectives:</b> To determine whether chest CT-scan in patients with cervical or endometrial cancer is of additional value for planning initial treatment and work-up. <b>Methods:</b> A retrospective analysis was performed of 465 patients diag…
Michael Agrez, Madhu Garg, Douglas Dorahy, Stephen Ackland
Background: It is known that active Src kinase promotes survival of ovarian cancer cell lines and inhibition of c-Src has been shown to restore sensitivity of drug-resistant human ovarian cancer cells to cisplatin. In this study we examined the effects of a 1…
Inès Ayadi Masmoudi, Amine Masmoudi, Nabil Toumi, Afef Khanfir, Mounir Frikha, Jamel Daoud
Obesity is associated with worse breast cancer outcomes in Western and Asian women. The present study was to determine the relation of body mass index (BMI) to disease-free survival (DFS) in Tunisian patients with operable breast cancer. We retrospectively re…
Takahito Suyama, Takeshi Ueda, Satoshi Fukasawa, Atsushi Komaru, Masayuki Kobayashi, Yukio Naya, Naoki Nihei, Tomohiko Ichikawa
Objective: This study aim to assess the efficacy and safety of sunitinib in Japanese patients with metastatic renal cell carcinoma (mRCC) in general clinical practice. Patients and Methods: Non-selected fifty eight Japanese patients with mRCC were treated wit…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).