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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Shimaa Ahmed, Mayada Fawzy, Khalid Rezk, Wessam Elshrif, Mohamed Alaa, Mohamed M. H. Abd Ellah
Background and objectives : Surgery is the primary therapy for localized gastric cancer, but even with the best results only 40% 5-year survival can be achieved with the use of postoperative adjuvant chemoradiotherapy. Preoperative therapy might help increase…
Elisabeth Seidel, Cynthia de Carvalho Fischer, Christopher Neumann, Anja Reutzel-Selke, Andreas Andreou, Joseph Gassner, Julia Gogolok, Peter Tang, Anja Schirmeier, Fritz Klein, Igor M. Sauer, Johann Pratschke, Marcus Bahra, Rosa B. Schmuck
Pancreatic adenocarcinoma (PDAC) and extrahepatic cholangiocarcinoma (ECC) are highly lethal malignancies with limited treatment options. Both a small subpopulation of cancer stem cells (CSC) and the deregulation of the notch pathway have been considered pote…
L. Döbrőssy, K. Lapis
In Hungary, the incidence and mortality from oral cancer is so high, that in the past decades it has attracted international attention. The mortality rates are the highest in Europe. As risk factors, smoking and alcohol drinking have a multiplicative role; in…
Melanie von Brandenstein, Julia Straube, Christina-Maria Geisbüsch, Luka Ozretić, Yasemin Ural, Verena Kirn, Wolfram Malter, Jochen W. U. Fries
Background: In breast cancer patients, a correlation between endothelin-1 (ET-1) and lymph node metastasis was found. While breast cancer with a positive ER status can be treated with Tamoxifen, several studies describe increasing Tamoxifen resistance in pati…
Daniela Sciancalepore, Maria Teresa Zingaro, Chiara Valentina Luglio, Carlo Sabbà, Nicola Napoli
Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer with a high mortality rate. While chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections represent the leading risk factors worldwide, the spreading of metabolic disorder…
Chi Wei Mok, Siew Kuan Lim, Su-Ming Tan
Introduction: The numbers of elderly patients with breast cancers are increasing with an ageing population, yet clinical research on these patients is still lacking. This study aims to examine the differences between elderly patients and their younger counter…
Hussein O. Soliman, Ahmed O. Touny, Reda H. Tabashy, Mohamed M. Abou El Moaty
Background: Hepatocellular carcinoma is a great problem that poses a huge burden upon any healthcare system. In Egypt it has shown a doubling in its incidence rate. This study intended to assess the different prognostic factors for the overall survival of HCC…
Hans W. Giertz
This study describes a novel model of cancer. Cancer is caused, according to this model, by two toxic molecules, COF 2 (carbonyl fluoride) and CS 2 (carbon disulfide). COF 2 acts as a catalyst and produces CS 2 . CS 2 acts as a catalyst and produces COF 2 . H…
Dina Ragab Diab Ibrahim, Mohamed Saad Hasaballah, Marwa Mohamed El-Begermy, Ahmed Abdel Aziz Ahmed, Soha Ahmed Abuelela
Background: Anemia is reported by many studies as an important risk factor for poor locoregional disease control and survival in head and neck carcinoma. We aimed to study the frequency and prognostic effect of low hemoglobin (Hb) level in head and neck squam…
Takafumi Yamano, Takeo Takahashi, Shuichi Ueno, Yuki Iigima, Keiichiro Nishimura, Kana Washizu, Rikana Soda, Nobuko Utsumi, Mikito Hondo, Munefumi Shimbo, Shogo Hatanaka, Masatsugu Haryu
Objective : We evaluated the effects of palliative radiotherapy for cancer recurrence or metastasis on patient QOL and psychophysiology. Materials and Methods : Sixty seven patients who received palliative radiotherapy between 2014 and 2015 were enrolled. Pat…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).