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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Suzan Wadi, Aaron R. Tipton, Jill A. Trendel, Sadik A. Khuder, Deborah J. Vestal
Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovari…
Georgia Kaiafa, Mattheos Bobos, Christos Savopoulos, Theocharis Koutsokostas, Kostas Kouskouras, Anna Kalogera-Fountzila, Thomas Zaraboukas, Ioannis Kostopoulos, Vassilis Perifanis, Stavros Hadjimiltiades
Short Retraction Notice The paper does not meet the standards of " Journal of Cancer Therapy ". This article has been retracted to straighten the academic record. In making this decision the Editorial Board follows COPE's Retraction Guidelines . The a im is t…
Lukman Cheraghvandi, Michael Silva, Charlie Cheng, Mauro Montalbano, Ali Shirafkan, Cristiana Rastellini, Luca Cicalese
Hepatocellular carcinoma (HCC) is a cancer with increasing incidence in the USA and high mortality rate. HCC is often difficult to treat due to underlying comorbidities such as cirrhosis. However, the application of loco-regional thermal ablation using radio…
Abdulqadir J. Nashwan, Nader I. Al-Dewik, Hisham M. Al Sabah, Mohamed A. Yassin, Shehab F. Mohamed, Nabil H. Omar, Dana B. Mansour, 1 1, 1 1, 1 1
Thalidomide is widely used in the treatment of multiple myeloma (MM). In recent years, several cases of pulmonary hypertension have been reported following treatment with thalidomide. The aim of this review was to evaluate the published literature on multiple…
Hui Huang, Shao-Yan Liu, Song Ni, Zong-Min Zhang, Xiao-Lei Wang, Zhen-Gang Xu
Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in…
Rie Tamaki, Fumio Amano, Tohru Hashida, Hironaga Satake, Hisateru Yasui, Akihito Tsuji, 1 1
Introduction: The survival rate of patients with Borrmann type 4 advanced gastric cancer is extremely poor in comparison to patients with gastric cancers of other histological types. An optimal chemotherapeutic regimen has yet to be determined. Patients and M…
Gallelli Luca, Falcone Daniela, Perri Mariarita, Erika Cione, Pelaia Girolamo, Mesuraca Maria, Terracciano Rosa, Spaziano Giuseppe, D’Agostino Bruno, Navarra Michele, Savino Rocco
In this study, we lowered the expression of HDAC2 protein, to evaluate the effects of simvastatin on the biochemical pathways involved in inflammatory and metastatic response. The model used is the non-small cell lung cancer line (GLC-82). T rypan blue staini…
Mohamed Lotayef, Yaser Abd Elkader, Amr Amin, Azza Taher, Ehab El-Kest, Momen Abdelall
Background: The optimal dose of palliative radiotherapy (RT) in symptomatic advanced lung cancer is unclear. Patients and methods: Patients with advanced NSCLC who were indicated for thoracic palliative RT with age up to 65 y and Performance Status (PS) 0 - 2…
Harioly Nirina Marie Osé Michael, Hoahy Rasoanandrasana, Raheritiana Todisoa Mahenina, Rasolonjatovo Anjaramalala Sitraka, Rakoto Alson Aimée Olivat, Rasamindrakotroka Andry
Introduction : Chronic Myeloid Leukemia is a myeloproliferative disorder affecting hematopoietic stem cells. The specific cytogenetic abnormality is translocation (9; 22) which leads to the BCR-ABL fusion gene. Methods : We did a bone marrow aspiration in our…
Ozan Haase, Ozan Angün, Ewan A. Langan, Franziska Hübner, Florian M. Vogt, Christoph Thorns, Detlef Zillikens, Patrick Terheyden
Objectives: Despite the array of new treatment strategies for the management of metastatic melanoma, the prognosis remains poor when immune checkpoint inhibition and targeted therapy options are exhausted. The antiangiogenic monoclonal antibody bevacizumab ha…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).