Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Kai Elliot Cham, Tania Robyn Chase, Bill Elliot Cham
Skin cancer accounts for more cases annually than all other cancers combined. Traditional skin cancer treatments often fail to distinguish between cancerous and healthy skin cells, resulting in less effective outcomes and poor cosmetic results. In contrast, C…
Henintsoa Murielle Rakotomalala, Diora Ronchalde, Tahina Razanadahy, Malala Razakanaivo, Tovo Harivony, Vonjy Angelo Andrianarison, Ny Ony Tiana Florence Andrianandrasana, Florine Rafaramino
Anaplastic thyroid carcinomas (ATCs) represent the final dedifferentiated stage of thyroid tumors. This is a severe and potentially lethal malignancy in humans. The clinical presentation is often striking, characterized by a rapidly enlarging, invasive, and c…
Malala Razakanaivo, Diora Ronchalde, Tahina Razanadahy, Tovo Harivony, Vonjy Angelo Andrianarison, Ny Ony Tiana Florence Andrianandrasana, Florine Rafaramino
Cervical cancer remains a major problem in Madagascar. Its occurrence affects all aspects of an individual’s life. Our study therefore assessed the impact of cervical cancer and its treatment on quality of life. A total of 24 cases of cervical cancer treated…
Hany Samy Attallah, Khaled Mohamed El-Shahat, Radwa Mohamed Hamed, Emad Mostafa, Aliaa Mahmoud, Ibraheem Haggag, Taha Derfy, Haytham A. Abdelkader
Background: Total Body Irradiation (TBI) is integral to conditioning regimens for hematological malignancies, traditionally requiring complex and costly setups. This study introduces a simplified approach utilizing Step-And-Shoot Intensity Modulation (SS-IMRT…
Duke Chen, Longhao Li
Purpose : Gastrointestinal stromal tumor (GIST) has been considered radiation-resistant and data on the radiotherapy for GIST in previous studies are lacking. The purpose of this article is to accumulate more experience in the application of radiotherapy for…
Yu Cai, Tingting Wang, Yuan Zhan
The Cold-Inducible RNA-Binding Protein (CIRBP) family plays a pivotal role in cellular stress responses and tumorigenesis. Recent studies have increasingly highlighted the expression alterations of CIRBP family members across various cancer types and their po…
Guea Ngbwa Ghislain, Ruth Rosine Meka’h Mapenya, Anne Marthe Maison Mayeh, Sandjong Ngoudjou Maxwell, Kenn Chi Ndi, Samba Odette Ngano, Guegang Goujou Emilienne
Background: Conventional radiation therapy is a technique that uses ionizing radiation to destroy tumor cells. Along with surgery, chemotherapy, hormonotherapy and target therapy, it plays a crucial role in the management of breast cancer by reducing its over…
Jinzhi Li, Yong Chen
Background: Pancreatic cancer is one of the most lethal malignancies, with postoperative recurrence severely affecting patient survival and prognosis. This study aims to develop and validate a clinical prediction model for postoperative recurrence in pancreat…
Lorena Munoz Guzman, William Manning, Valentina Zanfagnin, Kyle M. Devins, Fantine Giap, Andrea Russo, Annekathryn Goodman
Radiation-induced sarcomas (RIS) are rare but severe long-term complications of radiotherapy (RT). They typically arise years after exposure to ionizing radiation used to treat primary malignancies and complicate patient outcomes. Determining the risk associa…
Yu Cai, Yumei Wu
GSPT2 (G1 to S phase transition protein 2) has emerged as a critical regulator of the cell cycle and has garnered increased attention for its role in tumor biology in recent years. This review explores the multifaceted functions of GSPT2, highlighting its inv…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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