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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Masahide Ikeguchi, Yusuke Kohno, Kyoichi Kihara, Kazunori Suzuki, Kanenori Endo, Seiichi Nakamura, Takashi Sawada, Tetsu Shimizu, Tomoyuki Matsunaga, Yoji Fukumoto, Hiroaki Saito
Esophageal squamous cell carcinoma (ESCC) is a gastrointestinal carcinoma with a poor prognosis. To improve the survival of patients with this disease, neoadjuvant chemotherapy (NAC) has been introduced. However, the survival benefits of NAC or the correlatio…
Youssef A. Rezk, Kun Yang, Shoumei Bai, Karen Mclean, Carolyn Johnston, R. Kevin Reynolds, Ronald J. Buckanovich
Objective: Aldehyde dehydrogenase (ALDH) enzymatic activity identifies ovarian cancer stem-like cells. We investigated the antineoplastic activity of the ALDH inhibitor Disulfiram on bulk ovarian cancer cells and CD133 + /ALDH + cancer stem-like cells. Study…
Basel Refky, Anas Gamal, Emad Hamed, Adel Fathi, Mohammad Arafa, Sameh Roshdy, Khaled Gaballa, Essam Attia, Mohamed Abdelkhalek, Mohamed T. Hafez, Fayz Shahatto, Shadi Awny, Doaa Shokry, Gehad Tawfik
Background: Frozen section (FS) has a valuable role in the diagnosis of ovarian tumors. It is considered a pivotal point in guiding the surgical therapy, particularly in premenopausal women. In postmenopausal women, it may be required as well to avoid unneces…
Masataka Adachi, Kouji Banno, Iori Kisu, Megumi Yanokura, Moito Iijima, Takashi Takeda, Kiyoko Umene, Yuya Nogami, Eiichiro Tominaga, Daisuke Aoki
Long-term survival is the priority in treatment of patients with malignant tumors. In the field of gynecology, fertility preservation has also recently become an important objective due to improved treatment outcomes and different needs of patients. Methods f…
Julia R. Embry-Schubert, Lubna Qamar, Monique Spillman, Michael G. Kelly, Susan A. Davidson, Kian Behbakht
Study Design: Between January 2003 and June 2009, we collected fresh tumor and extracted high-quality RNA from the omental/peritoneal metastases of 47 patients with stage IIB-IV ovarian cancer. Clinical data were abstracted from the patients’ medical records.…
Gursaran Parshad Talwar, Rajyashree Sharma, Sonal Singh, Bhudev C. Das, Alok C. Bharti, Kirti Sharma, Priyanka Singh, Nishu Atrey, Jagdish C. Gupta
Carcinoma cervix is a major cancer of women killing 510,000 women every year worldwide. Human papilloma virus (HPV) infection of cervical cells initiates the transformation of the cervical cells to malignant stage. HPV-16 is the most frequent type of HPV caus…
Yutaka Yata, Masashi Namikawa, Tatsuya Ohyama, Takashi Ohsaki, Daisuke Kanda, Takeshi Hatanaka, Kei Shibuya, Jun Kubota, Hitoshi Takagi, Terumi Takahara, Teruo Yoshinaga
Background: Since advanced hepatocellular carcinoma (HCC) is potentially fatal, and patients’ quality of life (QOL) often deteriorates during their treatment, improving the prognosis and QOL of patients given chemotherapy is very important. In addition, cost-…
Xinfeng Li, Xiaofu Li, Wenrui Zhou, Gaoxiong Wang, Wei Wang
Aim: We measured Golgi protein73 (GP73), alpha-fetoprotein (AFP), and vascular endothelial growth factor (VEGF) expression in primary hepatic cancer (PHC) and assessed their clinical significance. Methods: Forty-five PHC and tumor-adjacent specimens and 14 no…
Sergio Hoyos, Jaime Chávez, Álvaro Duarte, Isabel Arenas, 1 1, 1 1
Introduction: Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and usually appears as part of liver cirrhosis (LC). Its management in the presence of LC is ideally with orthotopic liver transplantation. Surgical resection is indica…
Masaya Saito, Yoshihiko Yano, Hirotaka Hirano, Kenji Momose, Yuki Kawano, Masaru Yoshida, Takeshi Azuma, 1 1, 1 1
Aim: Transcatheter arterial chemoembolization (TACE) is thought to be a safe and effective treatment for hepatocellular carcinoma (HCC). However, in some HCC patients, it potentially shortens survival due to liver damage. We aimed to identify independent fact…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
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