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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Masahide Ikeguchi, Hiroaki Saito, Yasunari Miki, Takayuki Kimura
In Japan, S-1 plus cisplatin has become a standard regimen for the treatment of unresectable advanced gastric cancer; however, many patients are unable to continue effective chemotherapy because of the regimen’s severe side effects. Thus, control of drug toxi…
M. A. Nezami, Steven Hager, Jessica Garner
This article discusses the role of epithelial mesenchymal transition (EMT) and addresses the scientific merits on epigenetic regulation of EMT. The importance of EMT as a prognostic biomarker is explored and the rationale on application of multitargeted epige…
Hanan Ahmed Wahba, Hend Ahmed El-Hadaad, Waleed Nabeel Abozeed, Waleed Elnahas, Sameh Roshdy, Anas Gamal
Purpose: To evaluate patients with carcinoma of cervical stump (CCS) and analyse different clinico-pathologic factors affect prognosis. Patients and Methods: This study was carried out through review of clinical records of patients. Recorded data included inf…
Mario Guerrieri, Monica Ortenzi, Maria Michela Cappelletti Trombettoni, Indrit Kubolli, Roberto Ghiselli
Aim: Transanal endoscopic microsurgery (TEM) is an effective, minimally invasive alternative approach to traditional surgery. This study reviews the characteristics of a series of patients affected by early rectal cancer and discusses the results of this trea…
Kiyoshi Ohara, Katsuhiko Oyama, Akiyoshi Suzuki, Keizo Kawano, Shinji Morimoto, Ayako Okawa
Purpose: The impact of radiotherapy on bladder cancers heightened by increase of fraction size using three-dimensional conformal radiotherapy (3DCRT) was verified with biologically effective dose (BED, Gy10). Method: Twenty-five patients who were considered u…
Huihong Liang, Zhenwei Peng, Liangqi Cao, Shikun Qian, Zili Shao
Background: Retrospective comparison of stent patency and survival of patients with unresectable extrahepatic cholangiocarcinoma (CCA) treated by placement of self-expanding metal stents (SEMS) with or without endobiliary radiofrequency ablation (ERFA). Metho…
Hebatallah K. Ibrahim, Tarek Shouman, Azza Niazy Taher, Azza M. Nasr, Hesham Atef
Aim of Work: The aim of this work was to study the clinico-epidemiological characteristics of the patients with nasopharyngeal carcinoma (NPC), analyse the prognostic factors of the disease and to analyse the results of different treatment modalities and thei…
Hanan R. Nassar, Eman Z. Kandeel, Laila A. E. Hegazy, Amany M. Helal, Tarek Darwish, Soad A. Eltokhy
Background: The urokinase-type plasminogen activator system which consists of a proteinase (the urokinase-type plasminogen activator, uPA), a receptor (the urokinase-type plasminogen activator receptor uPAR or CD87) and inhibitors (PAI1) is enriched in severa…
H. Abbas, Shimaa Ahmed, Ahmed A. S. Salem, Mohamed Abou Elmagd Salem, Mahmoud Hussin, Wessam A. El Sherief
Purpose: Aim of this prospective, phase III trial was to compare the efficacy and toxicity of intravenous fluorouracil and oral capecitabine when given concurrently with radiation in adjuvant sitting for adenocarcinoma of the stomach after gastrectomy with D2…
James K. Russo, Daniel Grass, Kent E. Armeson, John Stahl, Tarek Dufan, John Reynolds, Aaron Luebke, Anand K. Sharma
Purpose: To investigate the toxicity, survival and patterns of failure in patients with advanced lung cancer treated with intensity modulated radiation therapy (IMRT) and chemotherapy. Methods and Materials: Retrospective chart review of 68 total patients: 46…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).