Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Mohamed Ben Mabrouk, Aida Ben Slama Trabelsi, Mohamed Ben Rejeb, Hanène Jaziri, Mehdi Ksiaa, Sassi Bouguizane, Badreddine Sriha, Ali Jmaa, Ali Ben Ali
Introduction: The aim of this study was to clarify the role of laparoscopy in the etiological diagnosis of exudative ascites of unknown origin in women. Materials and Methods: This was a prospective study from 2007 to 2012, including 83 women with exudative a…
Aaron J. Smith, John Oertle, Dino Prato
Metronomic dosing of chemotherapy was introduced in the early 2000s and has since gained recognition as a potential game changer in the manner of which chemotherapy can be administered. There are several known candidates for metronomic dosing of chemotherapy…
Zihuan Yang, Dandan Huang, Lekun Fang, Xingzhi Feng, Huanliang Liu, Lei Wang, Jianping Wang
Studies have shown that the tumor suppressor gene p53 may regulate thymidylate synthase (TS) activity in colorectal cancer (CRC) cells, hence attributed to chemo-resistance to 5-flurouracil in CRC. In this study, a total of 299 primary CRC patients who underw…
E. V. Cafà, B. Pecorino, G. Scibilia, P. Scollo
The aim of this study is to compare morbidity, surgical treatment and post-operative complications in elderly patients underwent surgery for advanced stage ovarian cancer, comparing to younger patients. Data of patients underwent surgery at the Department of…
D. Dequanter, M. Shahla, C. Aubert, Y. Deniz, P. Lothaire
Introduction: The goal of this study was to analyze the causes of death in patients with loco-regionally advanced squamous cell carcinoma (HNSCC) of the head and neck treated with multimodality treatment. Materiel: The mortality records of 138 advanced head a…
Tomoko Furuya, Yutaka Suehiro, Yukihisa Namiki, Kohsuke Sasaki, 1 1, 1 1
Copy number variations (CNVs) that are frequent in genome influence on susceptibility of various diseases including cancers. The present mini-review focuses on CNVs associated with susceptibility to the cancers. Since CNVs are different between cancer types,…
Oleg V. Bukhtoyarov, Denis M. Samarin, 1 1
Cancer is one of the leading causes of death in the world while the long-term prognosis is still unfavorable, despite the enormous efforts in the search for effective anti-cancer drugs. We think that the obstacle for creating of effective anti-cancer drugs co…
B. Ravi Shankar, Poojar Kiran, B. V. Madhavi, E. Vijay
Background: The prevalence of head and neck cancers in the world is around 57% and predominantly occurs in Asian countries. It accounts for 30% of all cancers in India. The cure rate of locally advanced squamous cell carcinoma of the head and neck (SCCHN) has…
Popoola Abiodun, Samira Makanjuola, Sowunmi Anthonia, Igwilo Adaeze, Mobolaji Oludara, Ibrahim Nasir, Omodele Foluso
Background: Breast cancer is one of the most common malignant diseases in women and adjuvant combination chemotherapy has been shown to reduce mortality from this disease. Adherence to medical treatment is a multifaceted issue that can substantially alter the…
Sekhar Pal, Kirat Kumar Ganguly, Shyamsundar Mandal, Jaydip Biswas, Amitava Chatterjee
Increased MMP-1 expression in various tumor cells is significantly correlated with cancer progression. Enhanced secreted and intracellular level of MMP-1 is found in breast cancer cell line MDA-MB-231 in presence of ECM glycoprotein fibronectin. To extrapolat…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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