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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Jimena Garibay-Garcia, Fernando Mejia-Sanchez, Eduardo Ramírez-San-Juan, Miriam V. Flores-Merino, Julieta Castillo-Cadena
The aim of this study was to evaluate the genotoxicity induced by cyclophosphamide-adriamycin treatment in breast cancer patients through the frequencies of Sister Chromatid Exchange (SCE), Replication Index (RI), Mitotic Index (MI) and Cell Proliferation Ind…
Tetsu Yamamoto, Ryoji Hyakudomi, Shinichi Sugimoto, Atsuo Tokuka, Yoshitoshi Sato, Satoshi Nagai, Hikota Hayashi, Masahikoo Igarashi, Kenji Takubo, Yoshitsugu Tajima
Oxaliplatin-based chemotherapy with bevacizumab is now widely used for colorectal cancer patients. This study evaluated the efficacy and tolerability of XELOX (capecitabine + oxaliplatin + leucovorin combined) therapy with or without bevacizumab in elderly pa…
Sundaram Subramanium, Venkatanarayan Balasundaram, Sridharan Nithya, Poojar Kiran
Background: Head and neck squamous cell carcinoma (HNSCC), is a common malignancy in the Indian Population. In locally advanced disease, chemoradiation is the standard of care. Although induction chemotherapy has been much studied, no clear benefit has been i…
Alex A. Prasad
A 50-year male patient presented to outpatient department with a mass on tongue associated with pain. A plain computerised tomography scan done on 17/01/13 revealed mild growth on lateral border of tongue with an enlarged jugulo-digastric lymph node measuring…
Rafael Mamprin Stopiglia, Wagner Eduardo Matheus, Patrick Vianna Garcia, Athanase Billis, Mariana Anteghini Castilho, Vitor Hugo Figueiredo de Jesus, Ubirajara Ferreira, Wagner José Fávaro
Purpose: The main objectives of this study were to characterize and compare the urothelial stem cells (healthy and cancer cells) and TLRs features in the urinary bladder of men without lesionsand with non-muscle-invasive and muscle invasive urothelial tumors.…
John David Rebibo, Emeric Lacarrière, Francois Xavier Nouhaud, Athmane Safsaf, Romain Caremel, Christian Pfister
Objectives: To evaluate the incidence of bladder cancer after nephro-ureterectomy (NUT) and determine the potential risk factors of bladder recurrence in patients with upper urinary tract urothelial carcinoma (UUT-UC). Materials and Methods: We retrospectivel…
Ekkasit Tharavichitkul, Sukon Prasitwattanaseree, Patrinee Traisathit, Cholthicha Thipmate, Somvilai Chakrabandhu, Pitchayaponne Klunklin, Wimrak Onchan, Razvan M. Galalae, Imjai Chitapanarux
Purpose: To report the retrospective study of external beam radiotherapy (EBRT) ± intravaginal brachytherapy (IVBT) as adjuvant treatment for endometrial cancer. Materials and Methods: From 2001-2009, 152 patients received complete surgical staging for endome…
Rakesh K. Mishra, Ashutosh K. Tewari
Inflammation is associated with various cancers, and plays a significant role in prostate cancer genesis including initiation, promotion, malignant conversion, invasion, and metastasis. While several studies posit an important role of inflammation in prostate…
Joel L. Schwartz, Alexander Munaretto, Sirlata Bagchi, David Crowe, Gonzalo Izaguirre
Background: Reported are increased risks for malignant transformation in human oral keratinocytes (HOK) from ethyl alcohol (ETOH), tobacco products or human papilloma virus oncogenic subtype 16 (HPV 16) infections. We examined various HOK cell responses to th…
C. P. Coyne, Toni Jones, Ryan Bear
The anti-metabolite chemotherapeutic, gemcitabine is relatively effective for a spectrum of neoplastic conditions that include various forms of leukemia and adenocarcinoma/carcinoma. Rapid systemic deamination of gemcitabine accounts for a brief plasma half-l…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
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