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Call for papersThe 2026 special issue on Climate & Health is open for submissions.Learn more
JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En…
Nicole A. Friel, Adam C. Rothenberg, Kurt Weiss
Pseudomyogenic hemangioendothelioma is a rare, recently described neoplasm that usually presents as multifocal lesions in a single extremity. The disease has demonstrated a high propensity for infiltrative growth and local recurrence but limited metastatic po…
Soichi Ejiri, Shin-ichi Kikuchi, Takahiro Tajino, Ryoichi Kawakami, Michiyuki Hakozaki, Shin-ichi Konno
Background: To provide patients with a superior quality of life (QOL) after their pelvic tumor resection, ensuring the stability of the trunk as well as satisfactory lower extremity function is important. Although microsurgical reconstructions for the pelvic…
Nicholas Greco, Trevor Schott, Xiaodong Mu, Adam Rothenberg, Clifford Voigt, Richard L. McGough III, Mark Goodman, Johnny Huard, Kurt R. Weiss
Osteosarcoma (OS), chondrosarcoma (CSA), and Ewings sarcoma (ES) are the most common primary malignancies of bone, and are rare diseases. As with all sarcomas, the prognosis of these diseases ultimately depends on the presence of metastatic disease. Survival…
Adam C. Rothenberg, Karl J. Henrikson, Suzanne C. Schiffman, Mark A. Goodman
Two cases are presented of patients with a history of metastatic rectal adenocarcinoma presenting with a painful joint effusion. Both cases are potential examples of metastasis to periarticular bone with local infiltration to the synovium, which is one propos…
Weiwei Shen, Yujie Niu, Helong Zhang
Tumors have already threatened human life and health for centuries, especially the recurrent of bone metastases is difficult to cure. Relapse can occur years to decades after resection of primary tumor. This phenomenon is common in many clinical cases and ani…
Ana Paula Montaldi, Julia Alejandra Pezuk, Elza Tiemi Sakamoto-Hojo, Luiz Gonzaga Tone, María Sol Brassesco
The outcome of patients with osteosarcoma has not significantly improved in the last three decades. Therefore, there is still a need for the development of more effective therapeutic strategies. Methoxyamine (MX) is a base excision repair (BER) inhibitor that…
Robert L. Elliott, Xian P. Jiang, Jonathan F. Head
I want to make it very clear at the beginning of this communication; this is a controversial opinion review. However, I believe it is time to rethink our approach to cancer research and therapy. Many cancer researchers, especially those involved in cancer gen…
Takanori Ayabe, Masaki Tomita, Eiichi Chosa, Makoto Ikenoue, Yukie Shirasaki, Kunihide Nakamura
Background: This retrospective study was to evaluate the efficacy and toxicity of gemcitabine plus carboplatin (GC regimen) and paclitaxel plus carboplatin (PC regimen) combination chemotherapy in elderly patients with non-small cell lung cancer. Methods: Sev…
Abdul Kasem, Christina Choy, Kefah Mokbel
Aim: To provide an up-to-date review of the literature on skin-sparing mastectomy (SSM) for breast cancer (BC). The article also reviews the oncological safety, effects of radiotherapy (RT) on immediate breast reconstruction (IBR), the indications for preserv…
Mohamed M. Rizk, Nermine H. Zakaria, Waleed G. Elshazely
Colorectal cancer represents the third cancer worldwide. Studies showed thatinsufficient levels of vitamin D may result in colorectal cancer. Genetic variations in genes controlling vitamin D activity would play a role in determining susceptibility to colorec…
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JCT is an international journal dedicated to the latest advancements in cancer therapy. The goal of this journal is to provide a platform for doctors and academicians all over the world to promote, share, and discuss various new issues and developments in cancer related problems. All manuscripts must be prepared in En… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
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Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
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