Microalbuminuria and Associated Factors in Diabetics at the CNHU-HKM of Cotonou
- 1 Endocrinology Teaching Unit, Faculty of Health Sciences of the University of Abomey-Calavi, Abomey-Calavi, Benin
- 2 Endocrinology Teaching Unit, Faculty of Health Sciences of the University of Abomey-Calavi, Abomey-Calavi, Benin
- 3 Endocrinology Teaching Unit, Faculty of Health Sciences of the University of Abomey-Calavi, Abomey-Calavi, Benin
Abstract
Diabetes mellitus is a disease of great frequency and is a major public health problem. Several complications can occur during the course of diabetes such as diabetic nephropathy, which starts with microalbuminuria in diabetic patients. This was a cross-sectional and analytical study which took place from 23 September to 23 December 2021 in the Endocrinology-Metabolism-Nutrition Department of the CNHU-HKM of Cotonou, Benin. We carried out an exhaustive census of the patients. Type 2 diabetic patients were included in the study, and 24-hour microalbumunuria, fundus examination and assessment of complications were performed. We identified 145 type 2 diabetic patients of whom 44 had positive microalbuminuria, i.e. a prevalence of 30.3%. There were 61 men and 84 women with a sex ratio of 0.72. The mean age was 59 years with extremes of 26 and 85 years. The complications identified in diabetics with positive microalbuminuria were Neuropathy (43.2%), Nephropathy (22.7%) and Retinopathy (20.5%). Factors associated with microalbuminuria in diabetics were: age, occupation, hypertension, diabetes imbalance, erectile dysfunction. Conclusion: Microalbuminuria is common in type 2 diabetes. It should be managed early to slow the progression of kidney disease to the end stage.
- World Health Organization (2016) Global Diabetes Report. WHO, Geneva, 88 p.
- (2008) Direction Nationale de la Protection Sanitaire Programme National de la Lutte contre les Maladies non Transmissibles. Final Report of the STEPS Survey in Benin.
- Djrolo, F., Paraïso, N., Diarra, O. and Makoutode, M. (2014) Diabetes Complications and Associated Factors in Type 2 Diabetic Patients in Cotonou. Journal of Diabetes Mellitus, 4, 311-315. https://doi.org/10.4236/jdm.2014.44043
- Hazoumé, R. (2014) Diabetic Nephropathy in Benin: Epidemiological, Clinical and Paraclinical Profile. 134 p.
- Agboton, et al. (2018) Prevalence and Determinants of Albuminuria in Type 2 Diabetes in Black Subjects in Southern Benin. Journal of Biology Clinic Society in Benin, 2, 20-23.
- Yameogo, N., Mbayé, A., Ndour, M., Kagambega, L., Ndiayé, M., Kane, M., et al. (2012) Study of Microalbuminuria and Other Cardiovascular Risk Factors in the Senegalese Type 2 Diabetes Population. Black African Medicine, 59, 303-308.
- Taleb, N., Salti, H., Al-Mokaddam, M., Merheb, M., Salti, I. and Nasrallah, M. (2008) Prevalence and Determinants of Albuminuria in a Cohort of Diabetes Patients in Lebanon. Annals of Saudi Medicine, 28, 420-425. https://doi.org/10.5144/0256-4947.2008.420
- Monabeka, H., Kibeke, P., Nsakala-Kibangou, N. and Yala, F. (2005) Prevalence of Microalbuminuria in a Congolese Diabetic Population (Type 2). Médecine d’Afrique Noire, 52, 482-487.
- Charfi, N., Kallel, N., Grine, S., Feki, M.M. and Abid, M. (2010) Aspects cliniques et évolutifs de la néphropathie diabétique à propos de 60 cas. Diabetes & Metabolism, 36, A55. https://doi.org/10.1016/S1262-3636(10)70215-9
- Ehud, U. (2008) Definition, Classification and Diagnosis of Diabetes and Other Categories of Dysglycaemia. Clinical Practice Guideline. Canadian Journal of Diabetes, 32, 10.
- Wang, S., Wang, L., Zhou, Y., et al. (2012) Prevalence and Control of Dyslipidaemia among Diabetic Patients with Microalbuminuria in a Chinese Hospital. Diabetes and Vascular Disease Research, 10, 169-178. https://doi.org/10.1177/1479164112454756
- The Microalbuminuria Captopril Study Group (1996) Captopril Reduces the Risk of Nephropathy in IDDM Patients with Microalbuminuria. Diabetologia, 39, 587-593. https://doi.org/10.1007/BF00403306
- Zelmanovitz, T., Gerchman, F., Balthazar, A.P., et al. (2009) Diabetic Nephropathy. Diabetology & Metabolic Syndrome, 1, Article No. 10. https://doi.org/10.1186/1758-5996-1-10