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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b…
Sergey Lupachyk, Hanna Shevalye, Pierre Watcho, Alexander Obrosov, Irina G. Obrosova, Mark A. Yorek
To determine the effect of Na+/H+-exchanger-1 on diabetic neuropathy in Type 2 diabetes Zucker diabetic fatty (ZDF) rats and lean controls were treated with cariporide (10 or 20 mg/kg/d), a Na+/H+-exchanger-1 inhibitor, for 4 weeks at 15 weeks of age. Neuropa…
Fang Fang, Minyu Gu, Lin Chen, Na Li, Xiaoying Ding, Yongde Peng
Background: Metabolic abnormalities have been widely studied in women with polycystic ovary syndrome (PCOS) and in patients with Type 2 diabetes mellitus (T2DM). However, there are few studies on the comparison of the metabolic disturbances between the two di…
Anissa Messaaoui, Sylvie Tenoutasse, Christian Mélot, Harry Dorchy
Background: Increased glomerular filtration rate (GFR) commonly develops in early diabetes and is closely correlated with the development of diabetic nephropathy. Objective: The aim was to study the relationship between GFR, C-peptide level and other paramete…
Satoru Sumitani, Shinya Morita, Reiko Deguchi, Koichi Hirai, Kosuke Mukai, Yoshihiko Utsu, Shunji Miki, Bunzo Sato, Hideji Nakamura, Soji Kasayama
β -cell dysfunction and decreased insulin sensitivity are believed to be two chief mechanisms that participate in deterioration of glycemic control in Type 2 diabetes. Meformin is widely accepted as the first-line oral agent in the treatment of Type 2 diabete…
Shuhei Nakanishi, Gen Takezawa, Yasuyuki Taooka, Katsuko Kikkawa, Naoko Matsumoto, Toru Hidaka
Aims: Epidemiologic evidence suggests that physical activity is associated with reduced risk of Type 2 diabetes. Walking is simple, effective, and by far the most prevalent physical activity among older adults. However, it is difficult to recognize and evalua…
Hirohisa Onuma, Kouichi Inukai, Masaki Watanabe, Yoshikazu Sumitani, Toshio Hosaka, Hitoshi Ishida
We investigated whether long-term glimepiride (GP) monotherapy improves insulin resistance and exerts a beneficial effect on beta cell function, as compared with glibenclamide (GC). One hundred Japanese Type 2 diabetic patients were randomly assigned to the G…
Mona Mansour, Randa Fayez Salam, Lila Rashed, Heba Salam
Objectives: Diabetic nephropathy is the leading cause of chronic kidney disease. The pathogenesis of DN remains incompletely understood. It has been recently demonstrated that inflammatory processes play a significant role in the development and progression o…
Mona A. K. Salem, Safinaz A. El Habashy, Dalia N. Toaima, Hassan S. Shaker, Osama M. A. H. Hetta, Jonair H. A. El Kafy
Background: Urinary bladder dysfunction is a major complication of diabetes mellitus and its mechanism has been attributed to autonomic and/or peripheral neuropathy. Objectives: Evaluation of diabetes mellitus and neuropathy effect on the urinary bladder dyna…
Patricia A. Metcalf, Susan Wells, Rod T. Jackson
Aims: Previous studies have suggested that the Framingham coronary heart disease risk prediction equation underestimates risk among people with Type 2 diabetes. We compared the 10-year absolute risks of coronary heart disease (CHD) using a Framingham equation…
John G. Spangler, Julienne Kirk
Worldwide, over 250 million people live with diabetes mellitus, a disease which has been described as an epidemic. While much is known about the cardiovascular risks associated with this condition, its association with cancer has been less appreciated at the…
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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).