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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b…
Roman Stavniichuk, Alexander A. Obrosov, Viktor R. Drel, Jerry L. Nadler, Irina G. Obrosova, Mark A. Yorek
Background: Increased mitogen-activated protein kinase (MAPK) phosphorylation has been detected in peripheral nerve of human subjects and animal models with diabetes as well as high-glucose exposed human Schwann cells, and have been implicated in diabetic per…
Hongbin Jin, Daniel C. Benyshek
A myriad of diabetes prevention programs are carried out worldwide to fight against the current type 2 diabetes (T2D) pandemic. The lack of a unified criterion for evaluating the efficacy of T2D prevention programs, however, makes the interpretation of preven…
Dotun Ogunyemi, Jun Xu, Arnold M. Mahesan, Steve Rad, Eric Kim, Jacqueline Yano, Carolyn Alexander, Jerome I. Rotter, Y.-D. Ida Chen
Objective: To profile the differential gene expression of the KEGG Adipocytokine Signaling pathway in omental compared to subcutaneous tissue in normal pregnancy. Study Design: Subjects included 14 nonobese, normal glucose tolerant, healthy pregnant women. Ma…
Javier Ena, Carlos R. Argente, Víctor González-Sánchez, Natividad Algado, Gema Verdú, Teresa Lozano
Recent Aims: New diagnostic methods are needed to detect peripheral arterial disease easier than using the ankle-brachial index measured by Doppler devices. We investigated whether the use of pocket pulse oximeters could meet sensitivity and specificity crite…
Susana Siewert, Irma González, Lucas Santillán, Roberto Lucero, Marta S. Ojeda, María S. Gimenez
Oxidative stress is associated with diabetes mellitus, a condition characterized by increased prevalence and progression rate of cardiovascular disease. NFE2-related factor 2 (Nrf2) is a master regulator of cellular detoxification responses and redox status.…
Joey Kaye, Pat Rapley, Gwen Babel, Suzanne Brown
AIM: To identify potential risk indicators for emerging adults transitioning to adult health care. BACKGROUND: Without maturity, independence, knowledge and motivation to manage their diabetes and successfully transition to adult healthcare, a proportion of e…
Lucy D. Mastrandrea
Recent Background: Development of obesity involves promotion of preadipocyte differrentiation. This study investigated the role that sphingosine kinases (SPHK) and ceramide-derived sphingosine 1-phosphate (S1P) play in adipocyte terminal differentiation. Mate…
Satoru Yamada, Ryo Hirai, Gaku Inoue, Yoshifumi Yamada, Junichiro Irie, Koichiro Atsuda, Toshikazu Yamanouchi
Background: Several studies have shown that twice-daily injections of premixed insulin analogs (MIX) could achieve comparable HbA1c levels to basal-bolus (BB) therapy. However, HbA1c does not necessarily reflect short-term glycemic fluctuations that may contr…
J. Charvat, J. Chlumsky, P. Svab, M. Peckova
Objectives : To evaluate the association of diastolic function of the left ventricle with flowme-diated dilatation (FMD) in uncomplicated Type 2 diabetes mellitus patients. Methods: Eighty-two uncomplicated Type 2 diabetic patients were examined by pulse and…
M. Abu Sayeed, Mir Masudur Rhaman, Nurunnahar Fayzunnessa, Parvin Akter Khanam, Tanjima Begum, Hajera Mahtab, Akhter Banu
Background s and Aims: Several epidemiological investigations revealed that the prevalence of Type 2 Diabetes Mellitus (T2DM) has been increasing in the adult population of Bangladesh. But the prevalence of diabetes among the children and adolescents in Bangl…
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JDM is an international journal dedicated to the current developments of Diabetes Mellitus, the broad scope will also include significant research in the fields of pathology and therapeutic innovations of diabetes itself, both type I and II. All manuscripts submitted to JDM must be previously unpublished and may not b… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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