Electrochemical Bioencapsulation of Nanomaterials into Collagen for Biomedical Applications
- 1 Microencapsulation and Nanomaterials Department, Southwest Research Institute, San Antonio, USA
- 2 Microencapsulation and Nanomaterials Department, Southwest Research Institute, San Antonio, USA
- 3 Microencapsulation and Nanomaterials Department, Southwest Research Institute, San Antonio, USA
- 4 Microencapsulation and Nanomaterials Department, Southwest Research Institute, San Antonio, USA
- 5 Microencapsulation and Nanomaterials Department, Southwest Research Institute, San Antonio, USA
Abstract
Here we reported a novel electrochemical encapsulation method to encapsulate various nanomaterials and bimolecules into collagen. The electrochemical encapsulation process involves assembling of collagen along with Nano/bio materi als using an isoelectric focusing mechanism. We have showed that a wide range of Nanomaterials such as carbon nano tubes, polymeric nanoparticles, magnetic calcium phosphate nanoparticles and biomolecules can be encapsulated into collagen. These novel collagen-based composite materials possess improved electric, mechanical, antimicrobial, mag netic, bioactive properties. Thus, this novel electrochemical encapsulation process offer s a means to fabricate novel bio materials for various biomedical applications such as tendon/ligament, nerve, skin tissue engineering, tendon / liga ment to bone grafts, and sutures, etc.
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