Background: The medical laboratory has a fundamental role in diagnosing diseases, following up and correcting treatment at the right time. The quality of laboratory result was affected by multiple factors through the stages of work. Objective: The study aimed to identify impact factors of poor quality management of clinical laboratories’ performance in Wad Medani city, Sudan. Methods: A descriptive cross-sectional study was followed; enrolled medical laboratories were seven governmental hospital laboratories and nine private laboratories. Medical laboratory design assessment data, personnel management and sampling, and general concepts of quality control were collected through the questionnaire. Results: The overall observed rates for proper design and structure, personal management, sample management, and quality control requirements in medical laboratories were 22.5%, 39.25%, 23.45%, and 30.50%, respectively. Conclusion: Several impact factors in design, person management, sampling and overall quality led to poor performance in medical laboratories in Wad Medany city.
Adam, M. I. (2019). Assessment of Laboratory Quality Management Practices at Public Hospitals Khartoum State, 2019. MSc. Thesis, International University of Africa.
Alam, M. S., Abdalla, S. E. B., & Jabeen, F. (2022). Assessment of Biosafety Practices in Clinical Laboratories in Khartoum State, Sudan. Journal of Biosciences and Medicines, 10, 93-103. https://doi.org/10.4236/jbm.2022.1011008
Ali, A. E. (2010). Evaluation Public Hospitals’ Laboratories Performance Using the Basic Standards of Total Quality Management-A Study in Khartoum State-Sudan. Ph.D. Thesis, Sudan University of Science and Technology.
Alifrangis, M., Lusingu, J. P., Mmbando, B., Dalgaard, M. B., Vestergaard, L. S., Ishengoma, D. et al. (2009). Five-Year Surveillance of Molecular Markers of Plasmodium falciparum Antimalarial Drug Resistance in Korogwe District, Tanzania: Accumulation of the 581G Mutation in the P. falciparum Dihydropteroate Synthase Gene. The American Journal of Tropical Medicine and Hygiene, 80, 523-527. https://doi.org/10.4269/ajtmh.2009.80.523
Atlaw, D., Sahiledengle, B., & Tariku, Z. (2021). Hepatitis B and C Virus Infection among Healthcare Workers in Africa: A Systematic Review and Meta-Analysis. Environmental Health and Preventive Medicine, 26, Article No. 61. https://doi.org/10.1186/s12199-021-00983-9
Bonini, P., Plebani, M., Ceriotti, F., & Rubboli, F. (2002). Errors in Laboratory Medicine. Clinical Chemistry, 48, 691-698. https://doi.org/10.1093/clinchem/48.5.691
Carraro, P., & Plebani, M. (2007). Errors in a Stat Laboratory: Types and Frequencies 10 Years Later. Clinical Chemistry, 53, 1338-1342. https://doi.org/10.1373/clinchem.2007.088344
Carter, J. Y. (2017). External Quality Assessment in Resource-Limited Countries. Biochemia Medica, 27, 97-109. https://doi.org/10.11613/BM.2017.013
Dacombe, R. J., Squire, S. B., Ramsay, A. R., Banda, H. T., & Bates, I. (2006). Essential Medical Laboratory Services: Their Role in Delivering Equitable Health Care in Malawi. Malawi Medical Journal, 18, 33-35. https://doi.org/10.4314/mmj.v18i2.10914
El-Amin, E. O., Elamin, O. E., Ahmed, R. A. M., Abdulla, A. K., Elamin, S. E., & Elhaj, H. I. (2013). Sero-Prevalence of Herpes Virus Infection in Sudanese Pregnant Women. Tropical Medicine & Surgery, 1, Article ID: 1000138. https://doi.org/10.4172/2329-9088.1000138
Elduma, A. H., & Saeed, N. S. (2011). Hepatitis B Virus Infection among Staff in Three Hospitals in Khartoum, Sudan, 2006-07. Eastern Mediterranean Health Journal, 17, 474-478. https://doi.org/10.26719/2011.17.6.474
Elsir, M. A., Almoshraf, I. A., Mustafa, M. A., Hussein, A. R. M. E., & Elkhidir, I. M. (2018). Evaluation of Immune Response to Hepatitis B Vaccine in Laboratory Workers, Khartoum, Sudan. Clinical Infectious Diseases, 2, Article No. 106.
Harb, R., Kachimanga, C., Bangura, M., Kanawa, S., Stratton, C. W., Milner Jr., D. A., & Eichbaum, Q. (2021). Providing Laboratory Medicine Training in a Low-Resource Setting: Lessons Learned From a Recent Experience in Sierra Leone. American Journal of Clinical Pathology, 155, 473-599. https://doi.org/10.1093/ajcp/aqaa131
Ivanov, O. (2011). Applications and Experiences of Quality Control. InTechOpen. https://doi.org/10.5772/612
Koplan, J. P., Puska, P., Jousilahti, P., Cahill, K., & Huttunen, J. (2005). Improving the World’s Health through National Public Health Institutes. Bulletin of the World Health Organization, 83, 154-157.
Krleza, J. L., Celap, I., & Vlasic Tanaskovic, J. (2017). External Quality Assessment in Croatia: Problems, Challenges, and Specific Circumstances. Biochemia Medica, 27, 86-92. https://doi.org/10.11613/BM.2017.011
Lippi, G., Banfi, G., Church, S., Cornes, M., De Carli, G., Grankvist, K. et al. (2015). Preanalytical Quality Improvement. In Pursuit of Harmony, on Behalf of European Federation for Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for Preanalytical Phase (WG-PRE). Clinical Chemistry and Laboratory Medicine (CCLM), 53, 357-370. https://doi.org/10.1515/cclm-2014-1051
Lippi, G., Bassi, A., Brocco, G., Montagnana, M., Salvagno, G. L., & Guidi, G. C. (2006). Preanalytic Error Tracking in a Laboratory Medicine Department: Results of a 1-Year Experience. Clinical Chemistry, 52, 1442-1443. https://doi.org/10.1373/clinchem.2006.069534
Lippi, G., Becan-McBride, K., Behúlová, D., Bowen, R. A., Church, S., Delanghe, J. et al. (2013). Preanalytical Quality Improvement: In Quality We Trust. Clinical Chemistry and Laboratory Medicine (CCLM), 51, 229-241. https://doi.org/10.1515/cclm-2012-0597
Lippi, G., Chance, J. J., Church, S., Dazzi, P., Fontana, R., Giavarina, D. et al. (2011). Preanalytical Quality Improvement: From Dream to Reality. Clinical Chemistry and Laboratory Medicine, 49, 1113-1126. https://doi.org/10.1515/CCLM.2011.600
Lippi, G., Guidi, G. C., Mattiuzzi, C., & Plebani, M. (2006). Preanalytical Variability: The Dark Side of the Moon in Laboratory Testing. Clinical Chemistry and Laboratory Medicine (CCLM), 44, 358-365. https://doi.org/10.1515/CCLM.2006.073
Mohamed, S. B., Ismail, A. M., Elmahdi, S. A., Abdorabo, A. A., & Ismail, I. M. (2016). The Accuracy and Performance of Different Clinical Laboratory Classes in the Sudan. Pyrex Journal of Biomedical Research, 2, 31-34.
Ndongmo, C. B. (2005). Clinical Laboratory Diagnostics in Africa. African Technology Development Forum Journal, 2, 21-22.
Petti, C. A., Polage, C. R., Quinn, T. C., Ronald, A. R., & Sande, M. A. (2006). Laboratory Medicine in Africa: A Barrier to Effective Health Care. Clinical Infectious Diseases, 42, 377-382. https://doi.org/10.1086/499363
Plebani, M. (2006). Errors in Clinical Laboratories or Errors in Laboratory Medicine? Clinical Chemistry and Laboratory Medicine (CCLM), 44, 750-759. https://doi.org/10.1515/CCLM.2006.123
Plebani, M. (2010). The Detection and Prevention of Errors in Laboratory Medicine. Annals of Clinical Biochemistry, 47, 101-110. https://doi.org/10.1258/acb.2009.009222
Plebani, M. (2015). Diagnostic Errors and Laboratory Medicine—Causes and Strategies. eJIFCC, 26, 7-14.
Rynning, M., Wentzel-Larsen, T., & Bolann, B. J. (2007). A Model for an Uncertainty Budget for Preanalytical Variables in Clinical Chemistry Analyses. Clinical Chemistry, 53, 1343-1348. https://doi.org/10.1373/clinchem.2007.086371
Wagar, E. A., Stankovic, A. K., Raab, S., Nakhleh, R. E., & Walsh, M. K. (2008). Specimen Labeling Errors: A Q-Probes Analysis of 147 Clinical Laboratories. Archives of Pathology & Laboratory Medicine, 132, 1617-1622. https://doi.org/10.5858/2008-132-1617-SLEAQA
Wilson, M. L., Gradus, S., & Zimmerman, S. J. (2010). The Role of Local Public Health Laboratories. Public Health Reports, 125, 118-122. https://doi.org/10.1177/00333549101250S215