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3D Bio-Printed Bone Scaffolds Incorporated with Natural Antibacterial Compounds
Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
- 1 Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
- 2 Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- 3 Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
- 4 Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
- 5 Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
- 6 Complex and Intelligent Research Center, East China University of Science and Technology (ECUST), Shanghai, China
Journal of Materials Science and Chemical Engineering·Volume 10 (2022)·Pages 63–69·Published 10 March 2022·DOI10.4236/msce.2022.103005
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Abstract
3D Bioprinting plays an irreplaceable role in bone tissue engineering. Shellac and curcumin are two natural compounds that are widely used in the food and pharmaceutical sectors. In this study, a new composite scaffold with good biocompatibility and antibacterial ability was manufactured by adding shellac and curcumin into the traditional bone scaffold through low-temperature three-dimensional printing (LT-3DP), and its impact on the osteoimmune microenvironment was evaluated.
KeywordsBone Tissue Engineering3D Printing Bone ScaffoldAntibacterialShellacCurcumin
- Hangge, P., Pershad, Y., Witting, A.A., Albadawi, H. and Oklu, R. (2018) Three-Dimensional (3D) Printing and Its Applications for Aortic Diseases. Cardiovascular Diagnosis and Therapy, 8, S19-S25. https://doi.org/10.21037/cdt.2017.10.02
- Li, G., Dong, J., Cao, Z., Wang, J., Cao, D., Zhang, X., et al. (2021) Application of Low-Dose CT to the Creation of 3D-Printed Kidney and Perinephric Tissue Models for Laparoscopic Nephrectomy. Cancer Medicine, 10, 3077-3084. https://doi.org/10.1002/cam4.3851
- Yu, W., Sun, X., Meng, H., Sun, B., Chen, P., Liu, X., et al. (2017) 3D Printed Porous Ceramic Scaffolds for Bone Tissue Engineering: A Review. Biomaterials Science, 5, 1690-1698. https://doi.org/10.1039/C7BM00315C
- Lin, S.J., LeGeros, R.Z., Rohanizadeh, R., Mijares, D. and LeGeros, J.P. (2003) Biphasic Calcium Phosphate (BCP) Bioceramics: Preparation and Properties. In: BenNissan, B., Sher, D. and Walsh, W., Eds., Key Engineering Materials, Vol. 240-242, 473-476. https://doi.org/10.4028/www.scientific.net/KEM.240-242.473
- Owen, G.R., Dard, M. and Larjava, H. (2018) Hydoxyapatite/Beta-Tricalcium Phosphate Biphasic Ceramics as Regenerative Material for the Repair of Complex Bone Defects. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106, 2493-2512. https://doi.org/10.1002/jbm.b.34049
- Shuai, C., Yuan, X., Yang, W., Peng, S., Qian, G. and Zhao, Z. (2021) Synthesis of a Mace-Like Cellulose Nanocrystal@Ag Nanosystem via In-Situ Growth for Antibacterial Activities of Poly-Llactide Scaffold. Carbohydrate Polymers, 262. https://doi.org/10.1016/j.carbpol.2021.117937
- Zhou, K., Dong, C.F., Zhang, X.L., Shi, L., Chen, Z.C., Xu, Y.L. and Cai, H. (2015) Preparation and Characterization of Nanosilver-Doped Porous Hydroxyapatite Scaffolds. Ceramics International, 41, 1671-1676. https://doi.org/10.1016/j.ceramint.2014.09.108
- Chang, G.H., Azar, D.A., Lyle, C., Chitalia, V.C., Shazly, T. and Kolachalama, V.B. (2019) Intrinsic Coating Morphology Modulates Acute Drug Transfer in Drug-Coated Balloon Therapy. Scientific Reports, 9. https://doi.org/10.1038/s41598-019-43095-9