An Interaction Study of Chloro and Alkyl Substituted Benzylamine with DPPH● through UV Spectrophotometric and Physicochemical Methods at T = (298.15, 303.15 and 308.15) K

Abstract

Radical scavenging activity (RSA) of chloro and methyl substituted benzylamine derivatives (BADs) has been studied using 1, 1-diphenyl-2-picrylhydrazyl free radical (DPPH?) through spectrophotometric and physico - chemical techniques at T = (298.15, 303.15 and 308.15) K. New experimental data on the density, sound velocity, isentropic and apparent molal compressibility of selected BADs + DPPH ● solutions as a function of temperature and concentration are reported. The results are discussed with regards to structure-activity relationship (SAR) principles of BADs. The relative deviations in RSAs varied with structural potentials of BADs which were ana lyzed by making a comparative study for both the spectrophotometric and physicochemical results.