The Effects of Fe<sub>2</sub>O<sub>3</sub> and B<sub>2</sub>O<sub>3</sub> on the Glass Structural, Thermal, <i>in Vitro</i> Degradation Properties of Phosphate Based Glasses — Oak Academic Publishing
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The Effects of Fe<sub>2</sub>O<sub>3</sub> and B<sub>2</sub>O<sub>3</sub> on the Glass Structural, Thermal, <i>in Vitro</i> Degradation Properties of Phosphate Based Glasses
Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
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Department of Technology, Sinoma Co., Ltd., Nanjing, China
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Department of Technology, Sinoma Co., Ltd., Nanjing, China
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Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
,
Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
,
Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
,
Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
,
Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
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Ningbo Nottingham New Materials Institute, The University of Nottingham Ningbo China, Ningbo, China
1 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
2 Department of Technology, Sinoma Co., Ltd., Nanjing, China
3 Department of Technology, Sinoma Co., Ltd., Nanjing, China
4 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
5 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
6 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
7 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
8 Ningbo Nottingham International Academy for the Marine Economy and Technology, The University of Nottingham Ningbo China, Ningbo, China
9 Ningbo Nottingham New Materials Institute, The University of Nottingham Ningbo China, Ningbo, China
Currently, phosphate based glasses have been potential future biomaterial for medical application due to excellent cytocompatibility and fully bioresorbability. In this study, phosphate based glass system with composition of 48P 2 O 5 -12B 2 O 3 -(25-X)MgO-14CaO-1Na 2 O-(X)Fe 2 O 3 (X = 6, 8, 10) and 45P 2 O 5 -(Y)B 2 O 3 -(32-Y)MgO-14CaO-1Na 2 O-8Fe 2 O 3 (Y = 12, 15, 20), w as prepared via a melting quenching process. The effect of replacing MgO with Fe 2 O 3 and B 2 O 3 on the structural, thermal, degradation properties of phosphate based glass w as investigated. Fourier Transform Infrared (FTIR) spectroscopy and Raman spectroscopy analysis confirmed the polymerisation of phosphate based glass network with addition of Fe 2 O 3 , thus the processing window was observed to increase whilst the dissolution rate was reduced, attributed to the formation of Fe-O-P cross-link. As the effect on the glass structure stability was demonstrated by both B 2 O 3 and MgO, the nonlinear variation of thermal stability and degradation behaviour was observed for glass system with substitution of MgO by B 2 O 3 . However, due to the lower dissolution rate of glass system when compared to the biocompatible phosphate based glass in preliminary study, the expected cytocompatibility could be confirmed in the downstream activities.
KeywordsPhosphate Based GlassBoronIronThermal PropertiesDegradation Study
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