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The Role of Microglia in Pediatric Neurological Disorders
Syosset High School, Syosset, USA
- 1 Syosset High School, Syosset, USA
Neuroscience and Medicine·Volume 16 (2025)·Pages 30–38·Published 10 January 2025·DOI10.4236/nm.2025.161004
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Abstract
Microglia, the central nervous system’s resident immune cells, play a pivotal role in brain development and function, particularly in pediatric neurological disorders. This review explores the molecular mechanisms underlying microglial dysfunction in conditions such as autism spectrum disorder, epilepsy, and juvenile neurodegenerative diseases, emphasizing their age-dependent roles. Therapeutic strategies targeting microglial activity are discussed, highlighting the need for precise, age-appropriate interventions to mitigate neurodevelopmental deficits and improve outcomes for affected children.
KeywordsMicrogliaPediatric NeurologyAutism Spectrum DisorderEpilepsyNeuroinflammationNeurodevelopment
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