Research ArticleOpen AccessGoogle Scholar indexed
Idiopathic Intracranial Hypertension in Sickle Cell Disease: A Paediatric Case Report
Department of Paediatrics, Queen Mary’s Hospital, Sidcup, UK
Department of Paediatrics, Queen Mary’s Hospital, Sidcup, UK
- 1 Department of Paediatrics, Queen Mary’s Hospital, Sidcup, UK
- 2 Department of Paediatrics, Queen Mary’s Hospital, Sidcup, UK
Neuroscience and Medicine·Volume 04 (2013)·Pages 215–216·Published 2 December 2013·DOI10.4236/nm.2013.44033
Copy link · social · email
Abstract
In this article , we present the case of a 12 - year - old girl with sickle cell disease (SCD) , who presented with the severe headache. She had bilateral 6th cranial nerve palsy and papilloedema. The common sickle cell - related vascular causes of headache were ruled out by neuro-imaging. She then had a lumbar puncture and was diagnosed with idiopathic in tracranial hypertension (IIH). This case demonstrates that IIH can affect younger children with SCD and should form a part of differential diagnosis when investigating causes of headache in SCD .
KeywordsSickle Cell DiseaseIdiopathic Intracranial HypertensionHeadache in Children
- I. Abu-Arefeh and G. Russell, “Prevalence of Headache and Migraine in School Children,” British Medical Journal, Vol. 309, 1994, pp. 765-769. http://dx.doi.org/10.1136/bmj.309.6957.765
- A. E. Niebanck, A. N. Pollock, K. Smith-Whitley, L. J. Raffini, R. A. Zimmerman, K. Ohene-Frempong and J. L. Kwiatowski, “Headache in Children with Sickle Cell Disease: Prevalence and Associated Factors,” Journal of Pediatrics, Vol. 151, No. 1, 2007, pp. 67-72.
- W. E. Dandy, “Intracranial Pressure without Brain Tumor,” Annals of Surgery, Vol. 106, No. 4, 1937, pp. 492-513. http://dx.doi.org/10.1097/00000658-193710000-00002
- D. Friedman and D. Jacobson, “Diagnostic Criteria for Idiopathic Intracranial Hypertension,” Neurology, Vol. 59, No. 10, 2002, pp. 1492-1495. http://dx.doi.org/10.1212/01.WNL.0000029570.69134.1B
- R. A. Avery, S. S. Shah, D. J. Licht, J. A. Huh, J. Boswinkel, M. D. Ruppe, A. Chew, R. D. Mistry and G. T. Liu, “Reference Range for Cerebrospinal Fluid Opening Pressure in Children,” The New England Journal of Medicine, Vol. 363, 2010, Article ID. 891-9-893
- E. Thomas, “Recurrent BIH Associated with Hemoglobin SC Disease in Pregnancy,” Obstetrics & Gynecology, Vol. 67, Suppl. 3, 1986, pp. 7S-9S. http://dx.doi.org/10.1097/00006250-198603001-00002
- M. Henry, M. C. Driscoll, M. Miller, T. Chang and C. P. Minniti, “Pseudotumor Cerebri in Children with Sickle Cell Disease: A Case Series,” Pediatrics, Vol. 113, No. 3, 2004, pp. 265-269. http://dx.doi.org/10.1542/peds.113.3.e265
- L. Segal and M. Discepola, “Idiopathic Intracranial Hypertension and Sickle Cell Disease: Two Case Reports,” Canadian Journal of Ophthalmology, Vol. 40, No. 6, 2005, pp. 764-767.
- D. Soler, T. Cox, P. Bullock, D. M. Calver and R. O. Robinson, “Diagnosis and Management of Benign Intracranial Hypertension,” Archives of Disease in Childhood, Vol. 78, No. 1, 1998, pp. 89-94. http://dx.doi.org/10.1136/adc.78.1.89
- J. O. Donaldson, “Pathogenesis of Pseudotumour Cerebri Syndromes,” Neurology, Vol. 31, No. 7, 1981, pp. 877-880. http://dx.doi.org/10.1212/WNL.31.7.877