Electroencephalographic Abnormalities in Patients with Idiopathic Insomnia
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Abstract
Objective: The main goal of the present research is to describe the electroencephalographic activity during sleep and the cyclic alternating pattern (CAP) on idiopathic insomniac patients. Methods: 22 idiopathic insomnia patients were included. Sleep recording included: fully conventional EEG recording (32 electrodes, with 16 channels getting ipsilateral bipolar recordings), EOG, EMG, EKG, thoracic and abdominal respiratory movements, nasal flow and oximetry. Results: Out of the 22 registered patients, 10 (45%) showed no electroencephalographic alteration, while 12 (55%) exhibited an electroencephalographic alteration (irritative activity). Concerning PSG variables, significant differences between groups (no EEG alteration and EEG alterations) were detected in: sleep latency, total sleep time, total wake time, sleep efficiency, light sleep percentage, slow waves sleep percentage and on the sub type A1 index of the cyclic alternant pattern CAP. Conclusions: The present data strongly suggest that within the population diagnosed with idiopathic insomnia, there is a subgroup in which the electroencephalographic alterations may play a critical role as the source of the sleep abnormality.
- J. Edinger, R. Bootzin, D. Buysse, C. Espie, L. Lack, C. Morin, D. Riemann, A. Spilman, E. Stepanski, Wohlgemuth W. Insom-nia. “The International Classification of Sleep Disorders. Diag-nostic and Coding Manual,” 2nd Edition, Westchester, Illinois, 2005. pp. 1-31.
- D. J. Taylor, K. L. Lichstein and H. H. Durrence, “Insomnia as a Health Risk Factor,” Behavioral Sleep Medicine, Vol. 1, No. 4, 2003, pp. 227-247. doi:10.1207/S15402010BSM0104_5
- M. M. Weissman, S. Greenwald, G. Ni?o-Murcia and W. C. Dement, “The Morbidity of Insomnia Uncomplicated By Psy-chiatric Disorders,” General Hospital Psychiatry, Vol. 19, No. 4, July 1997, pp. 245-250. doi:10.1016/S0163-8343(97)00056-X
- Z. De Saint Hilaire, J. Straub and A. Pelissolo, “Temperament and Character in Primary Insomnia,” European Psychiatry, Vol. 20, No. 2, 2005, pp. 188-192. doi:10.1016/j.eurpsy.2004.04.009
- “Diagnostic and Statistical Manual of Mental Disorders,” The American Psychiatric Association, 1980.
- M. G. Terzano, L. Parrino, M. C. Spaggiari, V. Palomba, M. Rossi, A. Smerieri, “CAP Variables and Arousals as Sleep Elec-troencephalogram Markers for Primary Insomnia,” Clinical Neurophysiology, Vol. 114, No. 9, September 2003, pp. 1715-1723.
- M. H. Bonnet and D. L. Arand, “The Consequences of a Week of Insomnia,” Sleep, Vol. 19, No. 6, July 1996, pp. 453-461.
- P. A. Lanfranchi, M. H. Pennestri, L. Fradette, M. Du- mont, C. M. Morin and J. Montplaisir, “Nighttime Blood Pressure in Normotensive Subjects with Chronic Insomnia: Implications for Cardiovascular Risk,” Sleep, Vol. 32, No. 6, 1 June 2009, pp. 760-766.
- Personal Communication, Jimenez Correa U, 2008.
- M. Terzano, L. Parrino, A. Smerieria, R. Chervinb, S. Chok-rovertyc, C. Guilleminaut, et al., “Atlas, Rules, And Recording Techniques for the Scoring of Cyclic Alternating Pattern (CAP) in Human Sleep,” Sleep Medicine Vol. 3, No. 2, 2002, pp. 187-199. doi:10.1016/S1389-9457(02)00003-5
- M. Terzano, L. Parrino, M. Sapaggiari, V. Palomba, M. Rossi and A. Smerieri, “CAP Variables and Arousals as Sleep Elec-troencephalogram Markers for Primary Insomnia,” Clinical Neurophysiology, Vol. 114, No. 9, September 2003, pp. 1715-1723.
- Standards of Practice Committee of the American Sleep Disor-ders Association Practice parameters for the Use of Polysom-nography in the Evaluation of Insomnia, 1995.