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Isoniazid-Induced Facial Tics in a Patient on Hemodialysis
Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
Centers for Disease Control and Prevention of Binzhou City, Binzhou, China
Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
- 1 Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
- 2 Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
- 3 Centers for Disease Control and Prevention of Binzhou City, Binzhou, China
- 4 Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
- 5 Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China
Neuroscience and Medicine·Volume 08 (2017)·Pages 25–28·Published 24 August 2017·DOI10.4236/nm.2017.83003
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Abstract
We report isoniazid (INH) induced tics in one male patient on hemodialysis at end-stage renal failure. He had pulmonary tuberculosis, accepted isoniazid, rifampin, ethambutol, pyrazinamide and rifampicin. He developed tics on both sides of the face. Surprisingly, he was also found the bilateral symmetrical frontal lobe and dentate nucleus hyperintensities on T2-weighted and T2 FLAIR MR imaging. After excluding other causes, INH induced neurological side effect was suspected so the drug was stopped, pyridoxine was added and hemoperfusion was applicated. Tics disappeared after 1 week.
KeywordsTicIsoniazidTuberculosisESRDHemodialysis
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