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Neurofibromatosis Type 1 in Four Children Cases
Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Unit of Neuroscience and Applied Nutrition, Laboratory of Nutrition, Health and Environment, Department of Biology, Faculty of Science, Kenitra, Morocco
Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
- 1 Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
- 2 Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
- 3 Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
- 4 Unit of Neuroscience and Applied Nutrition, Laboratory of Nutrition, Health and Environment, Department of Biology, Faculty of Science, Kenitra, Morocco
- 5 Pediatric Medical Emergency Department, Rabat Children’s Hospital, University Hospital of IbnSina, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco
Neuroscience and Medicine·Volume 08 (2017)·Pages 33–40·Published 24 August 2017·DOI10.4236/nm.2017.83005
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Abstract
Neurofibromatosis Type 1 (NF-1 or Von Recklinghausen disease) is an autosomal dominant genetic disease, characterized by an extreme variability of its clinical expression which is also found in the same family. Our work focuses on the exploitation of four cases of patients with NF-1 who were enrolled in the paediatric neurology consultation at Rabat Children’s Hospital. They are two infants and two children. Otherwise the diagnosis was made in front of the existence of café au lait and lentiginous spots in two boys, also the existence of café au lait spots and abnormalities in brain imaging in two girls. Thus an evolution was marked by a favorable outcome for three patients and neurological sequelae in one patient.
KeywordsNeurofibromatosis Type 1ChildrenCaféau lait SpotsLentiginous
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