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Neuroscience & Medicine is a peer reviewed international journal dedicated to the latest advancements of neuroscience. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to NM must be pre…
Chien-Ching Lee, Ya-Chun Chu, Chia-Chun Chuang, Chih-Yang Chen, Mei-Yung Tsou, Kwok-Hon Chan
Patients with Hallervorden-Spatz disease may be confronted by invasive procedure, like gastrostomy and thalamotomy for care of the status of extreme dystonia and rigidity. This rare disorder possesses potential perioperative risks, such as difficult airway ma…
Helmut Niederhofer, Kai von Klitzing
Background: Bright light therapy, an effective therapeutic option for depressive adults, could provide safe, economic, and effective rapid recovery also in adolescents. Method: This was a randomized cross-over trial, i.e. that 14 patients received first dim w…
Seiichi Yoshida, Toshiro Koike
Background: CD133 could be characterized as a “stem-like” cell subpopulation and an invasive tumor phenotype. The objectives of this study were to investigate the relationship of CD133 and other remodeling factors such as matrix metalloproteinases (MMP) in th…
Ogboi Sonny Johnbull, Babajide Farounbi, Ademola O. Adeleye, Olabunmi Ogunrin, Agu P. Uche
Background and Objective: Adherence to medication is the backbone to effectiveness of a therapy. In the absence of a definitive curative therapy, antiepileptic therapy is a key intervention aimed at prolonging and improving the quality of life of patients wit…
Peter K. Panegyres, Emily R. Atkins
Pharmacological studies reveal APP and Aβ have interactions with glutamate and calcium, cytokines, copper/zinc chelators, secretases and presenilins, nicotinic receptors, acetycholinesterase, neurotrophins, non-steroidal anti-inflame-matory drugs, monoclonal…
Makoto Hasegawa, Junichi Hada, Tetsuya Abe, Nao Ohtsu, Kousuke Honda, Masahiro Urade
In this study, we investigated whether increases in hippocampal blood flow (HBF) by tooth pulp stimulation (TPS) are mediated via the activation of cyclooxygenase-2 (COX-2). We measured mean arterial blood pressure (MABP) and HBF in urethane-anesthetized rats…
Sol M. Rodríguez-Colón, Fan He, Michele L. Shaffer, Xian Li, Alexandros N. Vgontzas, Edward O. Bixler, Rongling Wu, Duanping Liao
Limited population-based data from children are available to investigate the associations between insomnia and sleep duration in relationship to impaired cardiac autonomic modulation (CAM). Therefore, the objective of this study is to examine the cross-sectio…
Yoshiki Takeuchi, Yoshiki Matsumoto, Takanori Miki, Katsuhiko Warita, Zhi-Yu Wang, Kuldip S. Bedi, Tomiko Yakura, Jun-Qian Liu
It has been hypothesized that Rab3A, a small GTPase, may be closely involved in the process of dense core vesicle exocytosis in various cell types. This possibility was investigated by disrupting the expression levels of Rab3A-mRNA using a small interfering R…
John Smythies
This review covers recent advances in our knowledge of the role of a group of the most prominent neurotransmitters and neuromodulators in the field of the immune reactions of the body. The neurotransmitters and neuromodulators covered are the three catecholam…
Kazutaka Shigemi, Koji Tanaka, Kohsuke Hayamizu, Donald Michael Denbow, Mitsuhiro Furuse
L-Serine is considered a functional amino acid in the central nervous system, and induces sedation and hypnotic effects in some animal models of acute and chronic stress. Accordingly, while L-serine is a candidate anti-stress factor, the central mechanism of…
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Neuroscience & Medicine is a peer reviewed international journal dedicated to the latest advancements of neuroscience. The goal of this journal is to keep a record of the state-of-the-art research and to promote study, research and improvement within its various specialties. All manuscripts submitted to NM must be pre… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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