Clinical Application of Sex Hormone in Different Physiological Periods in the Diagnosis of Infertility Patients
- 1 Department of Clinical Laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- 2 Department of Andrology, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- 3 Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China
- 4 Department of Clinical Laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- 5 Department of Clinical Laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- 6 Department of Clinical Laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
- 7 Department of Clinical Laboratory, Reproductive Hospital of Guangxi Zhuang Autonomous Region, Nanning, China
Abstract
Background: Infertility is characterized by the inability to conceive after a year of regular unprotected intercourse. Aims: This study aimed to investigate the diagnostic value of sex hormone levels during different physiological periods in the diagnosis of infertility patients. Methods: From December 2019 to May 2021, a total of 93 infertility patients were admitted and selected as the observation group. Among them, 31 cases were in the follicular stage, 31 cases in the ovulation stage, and 31 cases in the luteal stage. Ninety-three healthy women for fertility evaluation due to male infertility were selected as the control group. The control group included 31 women in the follicular phase, 31 women in the ovulatory phase, and 31 women in the luteal phase. The levels of sex hormones (prolactin (PRL), luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E 2 ), testosterone (T), and progesterone (P)) during different physiological phases were compared between the observation and control groups. Results: The follicular phase showed no significant difference in LH levels between the observation group and the control group. The observation group showed higher levels of PRL and P compared to the control group, while the levels of FSH, E 2 , and T were lower in the observation group compared to the control group. The ovulation phase showed no significant difference in PRL levels between the two groups. The observation group showed lower levels of LH, FSH, E 2 , T, and P compared to the control group. The luteal phase showed no statistical difference in E 2 levels between the two groups. The observation group showed higher levels of PRL, LH, and FSH compared to the control group, while the levels of T and P were lower in the observation group compared to the control group. Conclusion: Infertile women show variations in hormone levels compared to the normal levels during the follicular phase, ovulatory phase, and luteal phase.
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