The Importance of Mathematical Models to Explore the Effects of Marijuana and Other Plant Based Products on Learning and Memory
- 1 Laboratory of Comparative Psychology and Behavioral Biology, Departments of Psychology and Integrative Biology, Oklahoma State University, Stillwater, OK, USA
- 2 Laboratory of Comparative Psychology and Behavioral Biology, Departments of Psychology and Integrative Biology, Oklahoma State University, Stillwater, OK, USA
- 3 Laboratory of Comparative Psychology and Behavioral Biology, Departments of Psychology and Integrative Biology, Oklahoma State University, Stillwater, OK, USA
Abstract
This article describes the use of the first order system transfer function for learning and memory studies involving consumption of marijuana and other plant based products. We provide detailed instructions on how the model can be used to analyze the performance of individual participants using a memory test developed by the senior authors. The importance of identifying possible learning and memory deficits of marijuana is paramount due to the growing number of states in the U.S. legalizing marijuana use for medicinal and recreational purposes. The model can also be extended to other plant based products purported to improve memory. While this article does not study the effect of marijuana, we provide details on how it can be used by illustrating its application on individuals consuming an amphetamine-like psychostimulant drug using our own memory test.
- Abramson, C.I. and Stepanov, I.I. (2007) The Application of a Mathematical Model for the Assessment of the Memorization Curve in Drug Addicts and Alcoholics. Journal of Drug Addiction, Education and Eradication, 3, 239-262.
- Stepanov, I.I., Abramson, C.I., Yates, K.F. and Convit, A. (2011) The Application of a Mathematical Model to the CVLT Learning Curve for Patients with Type 2 Diabetes Mellitus. In: Berjardt, L.V., Ed., Advances in Medicine and Biology, Nova Science Publishers Inc., New York, 1-47.
- Stepanov, I.I., Abramson, C.I., Hoogs, M. and Benedict, R.H.B. (2012) Overall Memory Impairment Identification with Mathematical Modeling of the CVLT-II Learning Curve in Multiple Sclerosis. Multiple Sclerosis International, 2012, Article ID: 312503. https://doi.org/10.1155/2012/312503
- Stepanov, I.I., Abramson, C.I., Wolf, O.T. and Convit, A. (2010) The Application of the First Order System Transfer Function for Fitting the California Verbal Learning Test Learning Curve. Journal of the International Neuropsychological Society, 16, 443-452. https://doi.org/10.1017/S1355617709991457
- Stepanov, I.I., Abramson, C.I. and Warschausky, S. (2011) Assessment of the Learning Curve from the California Verbal Learning Test—Children’s Version with the First-Order System Transfer Function. Child Neuropsychology, 17, 330-346. https://doi.org/10.1080/09297049.2010.541234
- Stepanov, I.I. and Abramson, C.I. (2008) The Application of the First Order System Transfer Function for Fitting the 3-Arm Radial Maze Learning Curve. Journal of Mathematical Psychology, 52, 309-319. https://doi.org/10.1016/j.jmp.2008.08.001
- Abramson, C.I. and Stepanov, I.I. (2012) The Use of the First Order System Transfer Function in the Analysis of Proboscis Extension Learning of Honey Bees, Apis mellifera L., Exposed to Pesticides. Bulletin of Environmental Contamination and Toxicology, 88, 559-562. https://doi.org/10.1007/s00128-011-0512-8
- De Stefano, L.A., Stepanov, I.I. and Abramson, C.I. (2014) The First Order Transfer Function in the Analysis of Agrochemical Data in Honey Bee (Apis mellifera L.): Proboscis Extension Reflex (PER) Studies. Insects, 5, 167-198. https://doi.org/10.3390/insects5010167
- Delis, D.C., Kramer, J.H., Kaplan, E. and Ober, B.A. (2000) California Verbal Learning Test (2nd Edition): Adult Version Manual. The Psychological Corporation, San Antonio.
- Zimprich, D. and Rast, P. (2009) Verbal Learning Changes in Older Adults across 18 Months. Aging, Neuropsychology, and Cognition, 16, 461-484. http://www.psypress.com/anc https://doi.org/10.1080/13825580902785663